Korean J Urol.  1986 Aug;27(4):505-510.

The Study of Ferritin Antigen and Carcinoembryonic Antigen in the Transitional Cell Carcinoma of Urinary Bladder by the Immunoperoxidase Technique

• Kim CS
• Kim CG

Abstract

Immunoperoxidase localization of carcinoembryonic antigen (CEA) and ferritin antigen was performed on tissue sections of 16 transitional cell carcinoma in the urinary bladder. On the basis of the cellular degree of atypias and mitotic figures and the architecture of the papillary pattern, transitional cell carcinoma was graded from I to III. The results are as follows: 1. Immunohistochemical localization of C.E.A in the transitional cell carcinoma, form Grade I to III shows intracytoplasmic positive reaction with increasing tendency in the superficial layer. 2. Immunohistochemical localization of ferritin in the transitional cell carcinoma, Grade I , shows entirely negative reaction. The transitional cell carcinoma, Grade III, shows more strong intracytoplasmic positive reaction rather than Grade II. 3. Immunohistochemical localization of CEA and ferritin in the infiltrating nests shows intracytoplasmic positive reaction anaplastic cells.

Keyword

ferritin antigen; CEA; bladder tumor

MeSH Terms

Carcinoembryonic Antigen*
Carcinoma, Transitional Cell*
Ferritins*
Immunoenzyme Techniques*
Urinary Bladder Neoplasms
Urinary Bladder*
Carcinoembryonic Antigen
Ferritins