J Korean Surg Soc.  1998 Aug;55(2):242-250.

Long-term Result of Radical Resection for Hilar Bile Duct Cancer

Affiliations
  • 1Department of Surgery, Inje University College of Medicine, Pusan Paik Hospital.

Abstract

Sixty patients with hilar bile duct cancer were operated on during a period of nine years. The tumor was resected in 45 patients (resection rate:75.0%). A hilar resection with regional lymph-node dissection was performed in 27 patients, and various types of hepatic resections were added in 18 patients. A potentially curative resection was achieved in 20 patients (curative resection rate:44.4%). There were two operative deaths (operative mortality:4.4%). The overall cumulative five-year survival rate was 25.6%. Six patients survived for more than five years. The survival was superior in patients with a curative resection and in those with a combined hepatic resection, but this result was statistically insignificant. Regional lymph-node metastasis, gross type, histologic grade, and perineural invasion were significant prognostic factors. We conclud that improved survival in hilar bile duct cancers can be achieved by a radical resection with acceptable morbidity and mortality.

Keyword

Hilar bile duct cancer; Radical resection

MeSH Terms

Bile Duct Neoplasms*
Bile Ducts*
Bile*
Humans
Mortality
Neoplasm Metastasis
Survival Rate
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