J Korean Soc Radiol.  2013 Nov;69(5):361-364. 10.3348/jksr.2013.69.5.361.

Pulmonary Invasive Mucinous Adenocarcinoma in an Asymptomatic 23-Year-Old Male: Presentation with a Large Cavitary Mass

Affiliations
  • 1Department of Radiology, Chonnam National University Hospital, Gwangju, Korea. seonhj@jnu.ac.kr
  • 2Department of Radiology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
  • 3Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.
  • 4Department of Thoracic and Cardiovascular Surgery, Chonnam National University Medical School, Gwangju, Korea.

Abstract

Pulmonary invasive mucinous adenocarcinoma (PIMA) formerly known as mucinous bronchioalveolar carcinoma is a relatively rare variant of pulmonary adenocarcinoma, but the incidence of this tumor is known to be rising. Imaging findings may include nodules, masses and lobar involvement of variable densities, but the majority present as air-space consolidation. We report a case of PIMA with radiological-pathological correlation in a 23-year-old male which presented as a large cavitary mass mimicking congenital cystic lung disease.


MeSH Terms

Adenocarcinoma
Adenocarcinoma, Mucinous*
Humans
Incidence
Lung
Lung Diseases
Male*
Mucins*
Potassium Iodide
Young Adult*
Mucins
Potassium Iodide

Figure

  • Fig. 1 A 23-year-old male with pulmonary invasive mucinous adenocarcinoma. A-C. Contrast enhanced mediastinal (A. axial image, B. coronal image) and lung window (C) setting chest CT shows a cavitary mass with internal air bronchogram (white arrows in C) and pseudo-cavitation (arrowhead in C), CT angiogram sign (white arrows in A, B) and surrounding daughter nodules (black arrows in C) in right lower lobe. D. FDG PET-CT scan shows mild FDG uptake (SUV = 1.9) of the mass. E. Photograph of the gross specimen demonstrates lobulated mass containing cystic lesion filled with gelatinous substance. F. On microscopy, the tumor cells arrange along alveolar septa (H&E, × 20). The tumor cells have a goblet cell appearance with copious intracytoplasmic mucin (Inset, H&E, × 100). Note.-FDG = 18F-fluorodeoxyglucose, PET = positron emission tomography, SUV = standardized uptake value


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