Korean J Urol.  2007 Mar;48(3):352-355. 10.4111/kju.2007.48.3.352.

A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter

• Yong DJ
• Lee KC
• Kim JG
• Joo M
• Cho IR

• KMID: 1997137
• DOI: http://doi.org/10.4111/kju.2007.48.3.352

Abstract

Neoplasms of the prostate usually metastasize to pelvic lymph nodes or bone, or directly invade the adjacent pelvic organs. Ureteral metastasis of a prostatic carcinoma, without ascending spread along the ureter, is very rare, with only a few having been reported from autopsy series. Herein, the case of a prostatic carcinoma, distantly metastasized to the unilateral ureter, is reported.

Keyword

Prostatic neoplasms; Metastasis; Ureter

MeSH Terms

Autopsy
Lymph Nodes
Neoplasm Metastasis
Prostate*
Prostatic Neoplasms*
Ureter*

Figure

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  Fig. 1 (A) Retrograde ureteral pyelogram showing a 1cm sized irregular narrowing of the right lower ureter, with a uniformly dilated ureter above the point of obstruction. (B) Ureteroscopy showing no mass.

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  Fig. 2 Selective washing cytology showing medium-sized, round to oval, atypical cells.

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  Fig. 3 Abdomino-pelvic computed tomography (CT) scan (enhanced) showing a 1cm sized enhancing mass, with ill defined ureteral wall thickening at the right lower ureter.

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  Fig. 4 The distal ureter reveals a segmental luminal narrowing, with firm consistency, measuring 5.3cm in length. An encircling submucosal mass, with luminal constriction (white arrow), is present. The proximal ureter and pelvis are diffusely dilated.

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  Fig. 5 (A) Low magnification view demonstrating transmural infiltration of the tumor cells, but with a relatively intact mucosa (H&E, ×10 & ×40). (B, C) Tumor cells have hyperchromatic nuclei and scanty cytoplasm, accompanied with frequent squeezing artifact (H&E, ×100 & ×200). (D) Immunohistochemical staining of the prostate-specific antigen (PSA) showing diffuse and focal positivities.

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