Korean J Urol.  2007 Mar;48(3):348-351. 10.4111/kju.2007.48.3.348.

Male Patients with the Diagnoses of Synchronous Prostate and Breast Cancer

• Lee CY
• Park CS
• Lee W
• Kwak HS
• Sol MY
• Chung MK

• KMID: 1997136
• DOI: http://doi.org/10.4111/kju.2007.48.3.348

Abstract

Prostate cancer and male breast cancer are similar in many ways, including the potential role of steroidal hormones in their pathogenesis and shared genetic abnormalities. However, the combination of these cancers in the same patient is rare. Herein, the case of a male patient, diagnosed with synchronous prostate and breast cancers, is reported.

Keyword

Synchronous neoplasms; Prostate cancer; Breast cancer

MeSH Terms

Breast Neoplasms*
Breast Neoplasms, Male
Breast*
Diagnosis*
Humans
Male*
Neoplasms, Multiple Primary
Prostate*
Prostatic Neoplasms

Figure

• 

  Fig. 1. (A) The tumor cell nests forming a solid mass, with pushing margin infiltrates into normal breast parenchyma (H&E, x100). (B) The tumor cells are large, with prominent nucleoli (H&E, x400).

• 

  Fig. 2. Immunohistochemical staining for the prostate-specific antigen (PSA) (A) and prostate associated protein antigen (PAP) (B) showing negative reactions in a breast ductal carcinoma.

• 

  Fig. 3. (A) The small compact tumor cell nests infiltrating into the normal prostatic parenchyma (H&E, x200). (B) The tumor cells have prominent basophilic nucleoli, which are characteristic of a prostatic adenocarcinoma (H&E, x400).

• 

  Fig. 4. Immunohistochemical staining for the prostate-specific antigen (PSA) (A) and prostate associated protein antigen (PAP) (B) showing

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