Kosin Med J.  2013 Dec;28(2):167-170. 10.7180/kmj.2013.28.2.167.

A Case of Type III Autoimmune Polyglandular Syndrome

• Gwoo S
• Choi YS
• Kim BK
• Park YH
• Kim KT
• Lee JS

• KMID: 1993576
• DOI: http://doi.org/10.7180/kmj.2013.28.2.167

Abstract

The autoimmune polyglandular syndromes (APS) are groups of syndromes comprising a combination of endocrine and nonendocrine autoimmune diseases. Among of those four types of APS, the main characteristics of the 3 APS are autoimmune thyroid diseases associated to other autoimmune diseases, excluding Addison's disease. Type 3 APS are also subdivided into 3A, 3B, 3C, and 3D. Recently, we experience a case of APS manifesting 3A, 3C, and 3D subtype. A 28-year-old woman developed type I diabetes. According to her medical history, she had Graves' disease, vitiligo, auimmune hemolytic anemia and systemic lupus erythematosus (SLE). The antoantibodies associated with Graves' disease, SLE, and type I diabetes showed positive findings. We report this case with literatures review.

Keyword

Autoimmune polyglandular syndromes; Graves' disease; Systemic lupus erythematosus; Type I diabetes

MeSH Terms

Addison Disease
Adult
Anemia, Hemolytic
Autoimmune Diseases
Female
Graves Disease
Humans
Lupus Erythematosus, Systemic
Thyroid Diseases
Vitiligo