Korean J Nephrol.
1999 Jul;18(4):644-647.
A Case of Nephrotic Syndrome Associated with Total Hydatidiform Mole
- Affiliations
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- 1Department of Internal Medicine, Chosun University Medical School, Kwangju, Korea.
- 2Department of Pathology, Chosun University Medical School, Kwangju, Korea.
Abstract
- A case study and review of nephrotic syndrome associated with a total Hydatidiform mole in 54- year-old female is presented. She has generalized edema, nephrotic range proteinuria(8.05gm/day), hypoalbuminemia(2.5g/dl) and high serum level of beta- hCG(200,000IU/L). Radiological investigations showed a 16-cm sized heterogenous enhanced mass in the uterus. A renal biopsy performed before evacuation of H-mole showed a focal segmental glomerulosclerosis. The complete remission of symptoms and signs of the nephrotic syndrom after evacuation of a molar tissue was achieved. A review of the literature revealed that this patient appears to be the first case of the FSGS with nephrotic syndrome associated with a total mole that remitted completely after the mole evacuation.
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