Korean J Urol.  2012 Dec;53(12):848-852. 10.4111/kju.2012.53.12.848.

Influence of Ureteral Stone Components on the Outcomes of Electrohydraulic Lithotripsy

Affiliations
  • 1Department of Urology, Hallym University College of Medicine, Seoul, Korea. cst326@paran.com

Abstract

PURPOSE
We evaluated the influence of urinary stone components on the outcomes of ureteroscopic removal of stones (URS) by electrohydraulic lithotripsy (EHL) in patients with distal ureteral stones.
MATERIALS AND METHODS
Patients with a single distal ureteral stone with a stone size of 0.5 to 2.0 cm that was completely removed by use of EHL were included in the study. Operating time was defined as the time interval between ureteroscope insertion and complete removal of ureteral stones. Ureteral stones were classified into 5 categories on the basis of their main component (that accounting for 50% or more of the stone content) as follows: calcium oxalate monohydrate (COM), calcium oxalate dihydrate, carbonate apatite (CAP), uric acid (UA), and struvite (ST).
RESULTS
A total of 193 patients (131 males and 62 females) underwent EHL. The mean operating time was 25.1+/-8.2 minutes and the mean stone size was 1.15+/-0.44 cm. Calcium oxalate stones accounted for 64.8% of all ureteral stones, followed by UA (19.7%), CAP (8.3%), and ST (7.2%) stones. The mean operating time was significantly longer in the UA group (28.6+/-8.3 minutes) than in the COM group (24.0+/-7.8 minutes, p=0.04). In multivariate analyses, the stone size was negatively associated with the odds ratio (OR) for successful fragmentation. UA as a main component (OR, 0.42; 95% confidence interval, 0.20 to 0.89; p=0.023) was also found to be significantly important as a negative predictive factor of successful fragmentation after adjustment for stone size.
CONCLUSIONS
The results of the present study suggest that successful fragmentation by URS with EHL could be associated with the proportion of the UA component.

Keyword

Lithotripsy; Ureteroscopy; Uric acid; Urinary

MeSH Terms

Accounting
Apatites
Calcium Oxalate
Carbon
Humans
Lithotripsy
Magnesium Compounds
Male
Multivariate Analysis
Odds Ratio
Phosphates
Ureter
Ureteroscopes
Ureteroscopy
Uric Acid
Urinary Calculi
Apatites
Calcium Oxalate
Carbon
Magnesium Compounds
Phosphates
Uric Acid

Reference

1. Basar H, Ohta N, Kageyama S, Suzuki K, Kawabe K. Treatment of ureteral and renal stones by electrohydraulic lithotripsy. Int Urol Nephrol. 1997. 29:275–280.
2. Verze P, Imbimbo C, Cancelmo G, Creta M, Palmieri A, Mangiapia F, et al. Extracorporeal shockwave lithotripsy vs ureteroscopy as first-line therapy for patients with single, distal ureteric stones: a prospective randomized study. BJU Int. 2010. 106:1748–1752.
3. Mugiya S, Nagata M, Un-No T, Takayama T, Suzuki K, Fujita K. Endoscopic management of impacted ureteral stones using a small caliber ureteroscope and a laser lithotriptor. J Urol. 2000. 164:329–331.
4. Defarges A, Dunn M. Use of electrohydraulic lithotripsy in 28 dogs with bladder and urethral calculi. J Vet Intern Med. 2008. 22:1267–1273.
5. See AC, Ng FC, Ch'ng HC. Electrohydraulic lithotripsy: an effective and economical modality of endoscopic ureteric lithotripsy. Aust N Z J Surg. 1997. 67:551–553.
6. Grocela JA, Dretler SP. Intracorporeal lithotripsy. Instrumentation and development. Urol Clin North Am. 1997. 24:13–23.
7. Mariani AJ. Combined electrohydraulic and holmium: YAG laser ureteroscopic nephrolithotripsy of large (>2 cm) renal calculi. Indian J Urol. 2008. 24:521–525.
8. Huang S, Patel H, Bellman GC. Cost effectiveness of electrohydraulic lithotripsy v Candela pulsed-dye laser in management of the distal ureteral stone. J Endourol. 1998. 12:237–240.
9. Noor Buchholz NP. Intracorporeal lithotripters: selecting the optimum machine. BJU Int. 2002. 89:157–161.
10. Yang SS, Hong JS. Electrohydraulic lithotripsy of upper ureteral calculi with semirigid ureteroscope. J Endourol. 1996. 10:27–30.
11. Tugcu V, Gurbuz G, Aras B, Gurkan L, Otunctemur A, Tasci AI. Primary ureteroscopy for distal-ureteral stones compared with ureteroscopy after failed extracorporeal lithotripsy. J Endourol. 2006. 20:1025–1029.
12. Daudon M, Lacour B, Jungers P. Influence of body size on urinary stone composition in men and women. Urol Res. 2006. 34:193–199.
13. Nishizawa K, Yamada H, Miyazaki Y, Kobori G, Higashi Y. Results of treatment of renal calculi with lower-pole fluoroscopically guided percutaneous nephrolithotomy. Int J Urol. 2008. 15:399–402.
14. Elashry OM, DiMeglio RB, Nakada SY, McDougall EM, Clayman RV. Intracorporeal electrohydraulic lithotripsy of ureteral and renal calculi using small caliber (1.9F) electrohydraulic lithotripsy probes. J Urol. 1996. 156:1581–1585.
15. Gettman MT, Segura JW. Management of ureteric stones: issues and controversies. BJU Int. 2005. 95:Suppl 2. 85–93.
16. Green DF, Lytton B. Early experience with direct vision electrohydraulic lithotripsy of ureteral calculi. J Urol. 1985. 133:767–770.
17. Begun FP, Jacobs SC, Lawson RK. Use of a prototype 3F electrohydraulic electrode with ureteroscopy for treatment of ureteral calculous disease. J Urol. 1988. 139:1188–1191.
18. Hsu TH, Lin SY, Lin CC, Cheng WT. Preliminary feasibility study of FTIR microscopic mapping system for the rapid detection of the composited components of prostatic calculi. Urol Res. 2011. 39:165–170.
19. Daudon M, Jungers P. Clinical value of crystalluria and quantitative morphoconstitutional analysis of urinary calculi. Nephron Physiol. 2004. 98:p31–p36.
20. Fazil Marickar YM, Varma L, Koshy P. Ultrastructural study of laminated urinary stone. Urol Res. 2009. 37:289–292.
21. Wirtz P, Krambeck AE, Handa SE, Terry C, Lingeman JE. Contralateral ureteroscopy performed at percutaneous nephrolithotomy: a unique evaluation of stone-free rates. J Urol. 2010. 184:2378–2382.
22. Seitz C, Tanovic E, Kikic Z, Fajkovic H. Impact of stone size, location, composition, impaction, and hydronephrosis on the efficacy of holmium:YAG-laser ureterolithotripsy. Eur Urol. 2007. 52:1751–1757.
23. Raney AM. Electrohydraulic cystolithotripsy. Urology. 1976. 7:379–381.
24. Grases F, Villacampa AI, Costa-Bauza A, Sohnel O. Uric acid calculi: types, etiology and mechanisms of formation. Clin Chim Acta. 2000. 302:89–104.
25. Hofbauer J, Hobarth K, Marberger M. Electrohydraulic versus pneumatic disintegration in the treatment of ureteral stones: a randomized, prospective trial. J Urol. 1995. 153(3 Pt 1):623–625.
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