Korean J Fertil Steril.
2001 Dec;28(4):301-306.
The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion
- Affiliations
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- 1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
- 2Institute for Clinical Research, College of Medicine, Pocheon CHA University, Pocheon, Korea.
Abstract
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OBJETIVE: To analyze the antithrombin III deficiency in patients with recurrent spontaneous abortion.
MATERIALS AND METHOD: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III.
RESULTS
There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT.
CONCLUSIONS
Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients.
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