J Korean Soc Radiol.  2014 May;70(5):369-372. 10.3348/jksr.2014.70.5.369.

Bilateral Metachronous Breast Cancer with Bilateral Recurrences: A Case Report and Literature Review

Affiliations
  • 1Department of Radiology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, Korea. sonyumee@naver.com
  • 2Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The incidence of bilateral breast cancer has been reported to range from 0.4% to 14%, and it increases gradually as a result of improved early detection capabilities and longer survival times. We report a rare case where the bilateral breast cancers occurred as a metachronous bilateral breast cancer with bilateral recurrences, detected by mammography, and the rapid growth of tumor that manifested as microcalcification and skin thickening within 3 months.


MeSH Terms

Breast
Breast Neoplasms*
Incidence
Mammography
Recurrence*
Skin
Ultrasonography

Figure

  • Fig. 1 Mammography of 51-year-old woman with a history of bilateral partial mastectomy. A. A screening mammogram of the right breast showed a few punctuate calcifications in a diffuse distribution categorized as category 2 (benign finding). The patient revisited the hospital after 3 months and complained of right breast swelling. B. A follow-up mammogram after 3 months showed developing pleomorphic microcalcifications (solid arrow) in a segmental distribution and skin thickening (arrowheads). C. Spot magnification view showed apparently pleomorphic microcalcifications with a segmental distribution (solid arrow) extending to the right subareolar area (dotted arrow), prompting a biopsy and the result of biopsy was invasive ductal carcinoma.

  • Fig. 2 Follow-up left spot magnification view during surveillance. A. Spot magnification of the left breast showed a few punctuate microcalcifications and macrocalcifications, which were categorized as category 3 (probably benign finding). B. Follow-up spot magnification view after 6 months showed an increasing number of suspicious pleomorphic microcalcifications (solid arrows).


Reference

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