J Korean Soc Transplant.  2014 Dec;28(4):236-240. 10.4285/jkstn.2014.28.4.236.

Papular Mucinosis in a Renal Transplantation Recipient

• Park JK
• Yu MY
• Koo G
• Kwak JH
• Lee JH
• Jung IS
• Oh H
• Park JS

• KMID: 1941319
• DOI: http://doi.org/10.4285/jkstn.2014.28.4.236

Abstract

Papular mucinosis (PM, scleromyxoedema) is a rare dermatologic disease. It is histologically characterized by a focal dermal deposit of mucin within the skin. Although PM is accepted as an idiopathic disease in most cases, some authors argued that it may be a cutaneous manifestation of a systemic disease. Here, we describe a 68-year-old male kidney transplantation recipient with a complaint of intractable itching sensation on the forehead. We diagnosed the skin lesions as PM, which were improved after cyclosporine dose reduction.

Keyword

Papularmucinosis; Kidney transplantation; Cyclosporine

MeSH Terms

Aged
Cyclosporine
Forehead
Humans
Kidney Transplantation*
Male
Mucins
Pruritus
Scleromyxedema*
Sensation
Skin
Cyclosporine
Mucins

Figure

• 

  Fig. 1. (A) Multiple, relatively well-demarcated, flesh or erythematous colored papules on the forehead. (B) Facial dome-shaped, skin-colored papules resolved 2 weeks after reduction of cyclosporine.

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  Fig. 2. A skin biopsy specimen shows (A) intact epidermis, deposition of mucinous materials (HE stain, ×40). (B) Deposition of mucinous materials between the collagen bundles and around the sweat glands (HE stain, ×100).

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  Fig. 3. Histopathologic specimens. (A) Alcian blue staining showing the deposits of mucin in the dermis (×40). (B) Alcian blue positive mucin deposits were found in the dermis (×100).

Reference

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