Korean J Urol.
1994 Jan;35(1):20-26.
Therapy and Outcome in 47 Cases of Wilms' Tumor
- Affiliations
-
- 1Department of Urology, Seoul National University, College of Medicine, Seoul, Korea.
- 2Department of Pediatrics, Seoul National University, College of Medicine, Seoul, Korea.
Abstract
- We studied to know The prognostic factors of Wilms' tumor who admitted to the Seoul National University Children's Hospital from May 1985 to July 1992. We treated Wilms' tumor with surgery, anticancer chemotherapy and radiation therapy according to National Wilms' Tumor Study protocol and analysed survival or relapse rate versus prognostic factors (age at diagnosis, histology, lymph node involvement and stage). As a result, during median follow-up period of 31 months, two year relapse free survival rate was 64% and 2-year overall survival rate was 79%. Two year overall survival rate was 100% in stage I, 83% in stage II and III, 60% in stage IV. This tumor stage was statistically significantly correlated with survival rate(P<0.05). However, other prognostic factor was not correlated with the survival rate(P> 0.05). We concluded that stage is more valuable prognostic factor than age, histology and lymph node involvement.
