Korean J Urol.  1979 Dec;20(6):599-602.

The Use of Methylene Blue for the Staining of Bladder Tumor

  • 1Department of Urology, Korea University Hospital, Seoul, Korea.


In 12 cases of bladder tumor, 30cc of 2% methylene blue was introduced into the bladder, one hour previous to the transurethral biopsy, T.U.R. or segmental resection of the bladder, for the purpose of the staining of tumor tissue, and the following results were obtained. 1. This method was especially useful for the difference of tumor tissue in the cases of cystitis with tumor. 2. Most of the tumor tissue which was not covered with bladder mucosa stained in the deep blue so that one can easily identify tumor tissues from normal mucosa. 3. On operation, tumor masses could be resected easily because of obvious demarkation between the tumor mass and normal mucosa of the bladder. 4. In conclusion, this method was helpful to identify tumor tissues and useful for the removal of tumor remnants.


bladder tumor; methylene blue

MeSH Terms

Methylene Blue*
Mucous Membrane
Urinary Bladder Neoplasms*
Urinary Bladder*
Methylene Blue
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