Korean Circ J.  1996 Oct;26(5):1058-1067. 10.4070/kcj.1996.26.5.1058.

A Case of Cardiac Amyloidosis with Complete Atrioventricular Conduction Block Treated by Permanent Pacemaker

• Jin SW
• Youn HJ
• Lim SH
• Kim YW
• Youn JH
• Chun HK
• Chung WS
• Kim JH
• Choi KB
• Hong SJ
• Lee KY
• Shim SI

• KMID: 1881500
• DOI: http://doi.org/10.4070/kcj.1996.26.5.1058

Abstract

In generalized amyloidosis, involvement of heart is not rare, but development fo severe conduction distubance in cardiac amyloidosis is a rare presentation in a clinical situation. We report the first case in Korea of cardiac amyloidosis with complete atrioventricular block, which was confirmed by endomyocardial biopsy. A 59-year-old woman was admitted due to drowsy mentality. We observed a severe atrioventricular conduction disturbance on the electrocardiogram and a marked hypertrophied ventricular wall and a granular sparkling appearance within the wall, a characteristic feature in cardiac infiltration of amyloidosis, on the echocardiography. Endomyocardial biopsy was performed and revealed extensive deposition of amorphous eosinophilic materials within the cardiac muscle cells. Polarizing illumination after Congo-red staining showed typical green birefrigence. We performed a insertion of permanent pacemaker(VVI type) for the treatment of complete atrioventricular block.

Keyword

Cardiac amyloidosis; Complete atrioventricular block; Permanent pacemaker

MeSH Terms

Amyloidosis*
Atrioventricular Block*
Biopsy
Echocardiography
Electrocardiography
Eosinophils
Female
Heart
Humans
Korea
Lighting
Middle Aged
Myocytes, Cardiac