Korean J Otolaryngol-Head Neck Surg.  2006 Jul;49(7):755-757.

Systemic Lupus Erythematosus Presenting as Multiple Cervical Mass

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea. diakonos@korea.ac.kr

Abstract

Systemic lupuserythematosus (SLE )can occur commonly in young women. The cause of SLE remains unknown. The initial symptoms include fever, chilling, or weight loss, and these nonspecific symptoms develop into skin rash, pericarditis, spleenomegaly or lymphadenopathy. The prevalence of lymphadenopathy ranges from 12% to 59% in lupus patients. Although Lupus lymphadenitis is a common finding, it is rarely the presenting manifestation since it can be pathologically indistinguishable from histiocytic necrotizing lymphadenitis (Kikuchi's disease). There have been sporadic reports of lupus lymphadenitis. We present a case of a 53 year old woman presenting cervical and inguinal lymph node enlargement and generalized skin rash. The clinical and pathologic aspects as well as differential diagnosis of this entity are reviewed.

Keyword

Histiocytic necrotizing lymphadenitis; Systemic lupus erythematosus

MeSH Terms

Diagnosis, Differential
Exanthema
Female
Fever
Histiocytic Necrotizing Lymphadenitis
Humans
Lupus Erythematosus, Systemic*
Lymph Nodes
Lymphadenitis
Lymphatic Diseases
Middle Aged
Pericarditis
Prevalence
Weight Loss
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