Korean J Gastrointest Endosc.  1998 Aug;18(4):553-559.

A Case of Angiocentric T-cell Lymphoma of the Esophagus

Affiliations
  • 1Department of Internal Medicine, Inha University, College of Medicine, Inchon, Korea.
  • 2Department of Pathology, Inha University, College of Medicine, Inchon, Korea.

Abstract

In this study we present a case of an angiocentric T-cell lymphoma (ACTL) which involve the esophagus. A 37-year-old male was admitted with dysphagia, odynophagia, and weight loss for 3 months. Two months before his admission, he had undergone on endoscopy with a biopsy. The first endoscopic findings revealed a large ulcerative lesion on the esophagus, although there had been no evidence of lymphoma upon microscopic examination. On the follow up endoscopic examination, this ulcerative lesion revealed progressive and destructive change. Histopathology of the third biopsied specimens showed large atypical lymphocyte infiltrates with angiocentric and angioinvasive features. Immunohistochemical studies revealed that the atypical (large) lymphocytes had T-cell phenotypes (CD3+, CD5+, and CD43+) and contained few reactive B-cells (CD20+), We assume that this is the first case of ACTL involving the esophagus and larynx.

Keyword

Angiocentric T-cell lymphoma; Esophagus; Angioinvasive

MeSH Terms

Adult
B-Lymphocytes
Biopsy
Deglutition Disorders
Endoscopy
Esophagus*
Follow-Up Studies
Humans
Larynx
Lymphocytes
Lymphoma
Lymphoma, T-Cell*
Male
Phenotype
T-Lymphocytes*
Ulcer
Weight Loss
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