Korean J Med Mycol.
1998 Jun;3(1):67-72.
A Case of Systemic Candidiasis with Skin Manifestations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- Candidiasis is the most common fungal infection complicating the course of the patients with hematologic malignancies. Although widespread organ involvement is characteristic of systemic candidiasis, report of skin involvement is rare. A 22-year-old man with acute lymphocytic leukemia showed fever and painful erythematous maculopapular eruptions on the whole body after combination chemotherapy of mitoxanthrone, cytosine arabinoside and etoposide. Histopathologic sections from the skin lesions showed sparse perivascular mononuclear cell infiltration in the dermis, and many blastospores and pseudohyphae within the dermis and subcutis. The patient died in spite of treatment with intravenous amphotericin B and oral flucytosine.
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