J Korean Soc Radiol.  2014 Feb;70(2):163-166. 10.3348/jksr.2014.70.2.163.

CT Findings of Lymphoepithelioid Cell Lymphoma: A Case Report

Affiliations
  • 1Department of Radiology, Wonkwang University School of Medicine and Hospital, Iksan, Korea. yjyh@wonkwang.ac.kr
  • 2Department of Radiology, Iksan Hospital, Iksan, Korea.
  • 3Department of Pathology, Wonkwang University School of Medicine and Hospital, Iksan, Korea.

Abstract

We report the computed tomography (CT) findings of a 70-year-old woman diagnosed with lymphoepithelioid lymphoma (Lennert's lymphoma). Neck, chest, and abdominal CT images revealed multiple enlarged lymph nodes, some of which showed heterogeneous mass or central low attenuation with peripheral rim enhancement. Although lymphoepithelioid cell lymphomas are very rare, they should be considered in the differential diagnosis of necrotic lymph nodes, particularly when combined with non-necrotic lymph nodes that show the typical radiologic features of lymphoma.


MeSH Terms

Aged
Diagnosis, Differential
Female
Humans
Lymph Nodes
Lymphoma*
Neck
Necrosis
Thorax
Tomography, X-Ray Computed

Figure

  • Fig. 1 Lymphoepithelioid cell lymphoma in a 70-year-old woman. A. Contrast-enhanced axial image of neck CT shows multiple enlarged lymph nodes in both neck spaces. The image demonstrates a necrotic lymph node at right level IIA (arrow). B. Contrast-enhanced axial image of chest CT shows multiple enlarged lymph nodes in both supraclavicular fossas. Note the central necroses in the left supraclavicular lymph nodes (arrows). C. Contrast-enhanced coronal image of chest CT also shows multiple necrotic lymph nodes with peripheral rim enhancement in the mediastinum and both pulmonary hila (arrows). D. Contrast-enhanced axial image of abdominal CT shows a markedly enlarged mesenteric lymph node (arrows) that contains solid and necrotic portions. E. Contrast-enhanced axial image of abdominal CT shows multiple enlarged lymph nodes (arrows). They show homogeneous enhancement and encase the mesenteric fat and vessels. F. Histopathologic exam shows neoplastic small cells that are admixed with confluent clusters of epithelioid histiocytes (arrowheads) (H&E, × 100). G. The tumor cells have nuclear irregularities and show frequent mitoses (arrows) and scattered Reed-Sternberg-like cells (arrowhead) (H&E, × 400).


Reference

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