J Korean Assoc Oral Maxillofac Surg.  2007 Dec;33(6):609-616.

Histomorphometric analysis of maxillary sinus augmentation with deproteinized bovine bone (Bio-Oss.) and various absorbable membrane

• Jang TH
• Jang YJ
• Kwon TG
• Lee SH

Abstract

PURPOSE: The aim of the present study was to evaluate the effect of Bio-Oss on bone formation in terms of healing period and type of membrane so that determine the most suitable condition for implant fixation in grafted maxilla. MATERIAL AND METHOD: Forty-five biopsy specimens from graft site were evaluated. Sinus lift was performed in the patients with reduced alveolar bone height(less than 5mm). The specimen was taken at the time of implant fixation, which was performed at least 5 months after the sinus lift procedure. All specimens were stained with HandE and Trichrome staining and evaluated histomorphometrically. RESULT: The results showed that Bio-Oss particle was in direct contact with newly formed bone in all cases. In the present study, the amount of newly formed bone and the residual bone substitute material were not statistically different according to various membrane and different healing period. There was no difference between the histological feature of the specimen of 5 and 31 months. No statistical significance was detected between male and female.
CONCLUSION
The result implies that Bio-Oss does not seem to be resorbed over time regardless of the type of the membranes. The further investigation is needed to clarify this issue with the extended period of follow-up.

Keyword

Sinus lift; Bio-Oss; Membrane; Histomophometric analysis

MeSH Terms

Biopsy
Bone Substitutes
Female
Follow-Up Studies
Hand
Humans
Male
Maxilla
Maxillary Sinus*
Membranes*
Osteogenesis
Transplants
Bone Substitutes