Infect Chemother.  2005 Jun;37(3):180-184.

VZV Pneumonia in Patients with Systemic Lupus Erythematosus

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea. paihj@hanyang.ac.kr
  • 2The Hospital for Rheumatic Disease, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

Varicella-zoster virus (VZV) is a member of the herpesviridae, which shares the characteristics of latent infection and reactivation. VZV causes two distinct clinical entities; varicella (chickenpox) and herpes zoster (shingles). Varicella pneumonia is the most common complication of adult varicella, especially in patients who are immunocompromised. We present two cases of VZV pneumonia occuring in patients with systemic lupus erythematosus (SLE) who were being treated with cytotoxic drugs and steroid. Both patients were treated with acyclovir and responses were good.

Keyword

Varicella-zoster virus pneumonia; SLE; Immunodeficiency

MeSH Terms

Acyclovir
Adult
Chickenpox
Herpes Zoster
Herpesviridae
Herpesvirus 3, Human
Humans
Lupus Erythematosus, Systemic*
Pneumonia*
Acyclovir
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