Korean J Pain.  2009 Aug;22(2):191-194. 10.3344/kjp.2009.22.2.191.

Acute Pseudoseptic Inflammatory Local Reactions after Intra-articular Hyaluronic Acid Injections in Patients with Knee Osteoarthritis

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea. hiitsme@hanmail.net
  • 2Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

Knee osteoarthritis is a common, but difficult problem to manage in primary care. Intra-articular hyaluronic acid injection has recently been frequently used for treating knee osteoarthritis. The adverse local reactions, except septic arthritis, following intra-articular hyaluronic acid injections are generally transient and not severe. Pseudoseptic arthritis is an extreme form of inflammatory arthritis that is not due to bacterial infection and it is important to distinguish this from true septic arthritis. In this article, we report 2 cases of acute pseudoseptic local reactions after intra-articular hyaluronic acid injections in patients with knee osteoarthritis.

Keyword

adverse effects; hyaluronic acid; injections; osteoarthritis

MeSH Terms

Arthritis
Arthritis, Infectious
Bacterial Infections
Humans
Hyaluronic Acid
Knee
Osteoarthritis
Osteoarthritis, Knee
Primary Health Care
Hyaluronic Acid
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