Yonsei Med J.  2012 Jul;53(4):859-862. 10.3349/ymj.2012.53.4.859.

Cerebral Salt Wasting Treated with Fludrocortisone in a 17-Year-Old Boy

• Choi MJ
• Oh YS
• Park SJ
• Kim JH
• Shin JI

• KMID: 1716890
• DOI: http://doi.org/10.3349/ymj.2012.53.4.859

Abstract

Cerebral salt wasting is characterized by inappropriate natriuresis and volume contraction with associated cerebral pathology. It is distinct from the syndrome of inappropriate antidiuretic hormone secretion, which is characterized by inappropriate retention of free water. We report a patient with a porencephalic cyst who developed cerebral salt wasting. His initial treatment was supplementation of water and salt, which did not improve natriuresis or volume contraction. Fludrocortisone administration effectively managed the cerebral salt wasting.

Keyword

Cerebral salt wasting; hyponatremia; fludrocortisone

MeSH Terms

Adolescent
Fludrocortisone/*therapeutic use
Humans
Hyponatremia/*drug therapy
Male
Natriuresis/physiology
Sodium Chloride/therapeutic use

Figure

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  Fig. 1 The computed tomography shows a porencephalic cyst in the left parieto-occipital and right frontal areas, showing the inserted cysto-parietal shunt.

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  Fig. 2 (A) Changes in serum Na level following fludrocortisone use (mmol/L). (B) Changes in random urine Na level following fludrocortisone use (mmol/L). Na, sodium.

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