Korean J Pediatr.  2014 Mar;57(3):110-116. 10.3345/kjp.2014.57.3.110.

Clinical utilization of cord blood over human health: experience of stem cell transplantation and cell therapy using cord blood in Korea

Affiliations
  • 1Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea. cord@hanyang.ac.kr

Abstract

Cord blood (CB) has been used as an important and ethical source for hematopoietic stem cell transplantation (SCT) as well as cell therapy by manufacturing mesenchymal stem cell, induced pleuripotential stem cell or just isolating mononuclear cell from CB. Recently, the application of cell-based therapy using CB has expanded its clinical utility, particularly, by using autologous CB in children with refractory diseases. For these purposes, CB has been stored worldwide since mid-1990. In this review, I would like to briefly present the historical development of clinical uses of CB in the fields of SCT and cell therapy, particularly to review the experiences in Korea. Furthermore, I would touch the recent banking status of CB.

Keyword

Cord blood; Transplantation; Cell therapy

MeSH Terms

Cell- and Tissue-Based Therapy*
Child
Fetal Blood*
Hematopoietic Stem Cell Transplantation
Humans
Korea
Mesenchymal Stromal Cells
Stem Cell Transplantation*
Stem Cells*
Transplantation
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr