Korean J Dermatol.  1982 Aug;20(4):557-561.

A Case of Epidermolytic Hyperkeratosis

Abstract

Epidermolytic hyperkeratosis is a rare disease which is extremely variable in its severity. In some patients it may be so severe and generalized during the neonatal period as to be lifethreatening, in others, it is relatively inconspicuous. A bullous eruption is the characteristic finding of the epidermolytic hyperkeratosis The bullous episodes soon become less frequent and more localized and may eventually cesse, but continue into adult life after the age of 20 years in at least 20% of cases. A case of epidermolytic hyperkeratosis is represented. The patient was a 25-year-old male who had ichthyosiform erythroderma and the frequent episades of bullous eruption. The bullous eruption had been subsided under the treatment with oral penicillin administration. The histopathological features of the bullous lesion on his abdomen revealed the features of epidermolytic hyperkeratosis.


MeSH Terms

Abdomen
Adult
Blister
Dermatitis, Exfoliative
Humans
Hyperkeratosis, Epidermolytic*
Male
Penicillins
Rare Diseases
Penicillins
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