Korean J Dermatol.  1980 Dec;18(6):613-617.

A Case fo Elephantiasis Neuromatosa

Abstract

Elephantiasis neuromatosa is one of 3 types of cutaneous tumors in Von Recklinghausen's disease. This 28 year-old male patient visited for adult-fist sized tumor associated with hairy pigmented patch on right antecubital fossa, and various sized tumors and cafe-au-lait spots on whole body of about 27 years duration. Past history was noncontributory. Family history revealed that his father and son had similar manifestations. Laboratory findings were noncontributory. Histopathology of cafe-au-lait spot and hairy pigmented patch revealed increase of melain in basal cell layer of the epidermis and increase in the concentratiton and activity of the melanocytes in basal cell layer of the epidermis. Histopathology of the mass revealed slightly thin, wavy fibrs lying in loosely textured strands extending in varying directions and a fairly large number of nuclei that are ovel to spindle-shaped and fairly uniform in size.


MeSH Terms

Adult
Cafe-au-Lait Spots
Deception
Elephantiasis*
Epidermis
Fathers
Humans
Male
Melanocytes
Neurofibromatosis 1
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