J Korean Pediatr Soc.  1980 May;23(5):406-412.

Two Cases of Rapidly Progressive Glomerulonphritis treated with ?ulse Methylprednisolone Therapy

• Chung SP
• Kim H
• Kim KT

Abstract

Tow patients with severe glomerulonephitis and their serum creatinine clearance of 6.0ml/min/1.73m2 in case 2 were treated with high dosage intravenous methylprednisolone, 30mg/kg given over one hour period on each of six slternate days. Follwing the ?ulse therapy, both patients with rapidly deteriorathin renal funtion began to inprove and theit serum creatinine clearance levels showed over douvble by sixdays In both patients treated early in the curse of their disease, creatinine clearance increased to 80ml/min/1.73m2 in case 2 after one year follow-up and in recent study, clinical and laboratory findings are within normal limit.

MeSH Terms

Creatinine
Follow-Up Studies
Humans
Methylprednisolone*
Creatinine
Methylprednisolone