Korean J Cytopathol.  1990 Dec;1(2):152-157.

Fine Needle Aspiration Cytology of Myxodi Chondrsarcoma of Pleura: A Case Report

• Myong NH
• Cho KJ
• Jang JJ
• Zo JI
• Shim YM

Abstract

A 70-year-old female who was diagnosed as myxoid chondrosarcoma by fine needle aspiration of a pleural mass is described. She presented with left chest discomfort of 4 months' duration and aggravating dyspnea and chest pain for 2 months. Chest X-ray and CT scan revealed a large lobulated low density mass invading chest wall at the left pleural cavity and massive pleural fluid. Fine needle aspiration was done under the impression of mesothelioma or metastatic cancer. The aspirates from the mass were very cellular and composed of isolated or clustered forms of large plump cells. Abundant cytoplasm was bluish opaque and the margin was rounded in the isolated cells, whereas clustered cells show ill-defined cell borders and aggregating tendency. The nuclei were eccentric, round to ovoid, and had fine chromatin pattern and multiple small nucleoli. Cellular pleomorphism or mitotic figure was not definite. These findings were consistent with cytologic features of chondrosarcoma. Final diagnosis was confirmed as myxoid chondrosarcoma by mediastinoscopic biopsy and the tumor showed strong positivity for S-100 protein.

Keyword

Myxoid chondrosarcoma; Pleural mass; Aspiration cytology

MeSH Terms

Aged
Biopsy
Biopsy, Fine-Needle*
Chest Pain
Chondrosarcoma
Chromatin
Cytoplasm
Diagnosis
Dyspnea
Female
Humans
Mesothelioma
Pleura*
Pleural Cavity
S100 Proteins
Thoracic Wall
Thorax
Tomography, X-Ray Computed
Chromatin
S100 Proteins