J Korean Soc Ther Radiol.  1986 Dec;4(2):147-154.

Result of Postoperative Radiotherapy of the Rectal Cancer

Affiliations
  • 1Department of therapeutic Radiology, College of Medicine, Seoul National University, Korea.
  • 2Department of Surgery, College of Medicine, Seoul National University, Korea.

Abstract

To assess the effect of postoperative radiotherapy on tumor recurrence and patient survival, 133 patients who received adjuvant postoperative radiotherapy for adenocarcinoma of the rectum were retrospectively analyzed. Sixty-one percent of the patients were in stage C2 by Astler-Coller staging system. A significant statistical difference was noticed in failure rates for lymph node negative vs lymph node positive patients;26%(9/35) vs 50%(49/98). The incidence of local failure was found to be strongly dependent on the pathologic stages; with 9%(3/35) of recurrence in stage B and 21% (21-98) in stage C. Distant metastasis has occurred in 29% (38/133) of the patients; 2% (7/35) in stage B and 32%(31-98) in stage C. The actuarial Survival at 3 years for patients in stage B2, stage C1, and stage C2, were 78%, 47%, and 38%, respectively. In conclusion, the postoperative adjuvant radiotherapy for rectal carcinoma appears to reduce local recurrence significantly.

Keyword

Rectal cancer; Post-op radiotherapy

MeSH Terms

Adenocarcinoma
Humans
Incidence
Lymph Nodes
Neoplasm Metastasis
Radiotherapy*
Radiotherapy, Adjuvant
Rectal Neoplasms*
Rectum
Recurrence
Retrospective Studies
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