J Korean Radiol Soc.  2002 Sep;47(3):285-292. 10.3348/jkrs.2002.47.3.285.

Well-Differentiated Hepatocellular Carcinoma: Triple-Phase Helical CT Findings

Affiliations
  • 1Department of Radiology and Gastrointestinal Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. shkim@smc.samsung.co.kr
  • 2Department of Radiology, Gachon Medical College Gil Medical Center, Korea.
  • 3Department of Radiology, College of Medicine, Inha University, Korea.

Abstract

PURPOSE: To determine the imaging characteristics of well-differentiated hepatocellular carcinomas (HCCs), as seen at triple-phase helical CT.
MATERIALS AND METHODS
Thirty-eight well-differentiated HCCs in 29 patients who underwent surgical resection comprised our study population. Triple-phase helical CT images were obtained at 30 seconds, 70 seconds, and 3 minutes after contrast injection, and HCCs were divided into four groups according to their size: smaller than 1 cm (n=12), 1-2 cm (n=15), 2-4 cm (n=8), and larger than 4 cm (n=3), The enhancement patterns of HCCs at triple-phase helical CT were retrospectively analysed.
RESULTS
In the smaller than l cm group, the most common enhancement pattern at all three phases was iso-attenuation (n=8; 67%). In the 1-2 cm group, iso-attenuation (n=10; 67%) was most common during the arterial phase and slightly low attenuation during the portal and equilibrium phases while in the 2-4 cm group, high attenuation (n=6; 75%) was most common during the arterial and portal phases, and low attenuation during the equilibrium phase (n=6; 75%). Two (67%) of three cases in the larger than 4 cm group demonstrated low, including fatty, attenuation. The detection rate was 33% (4/12) in the smaller than 1 cm group, 87% (13/15) in the 1-2 cm group and 100% (11/11) in the 2-4 cm and larger than 4 cm groups.
CONCLUSION
At triple-phase helical CT, the enhancement patterns of well-differentiated HCCs were diverse, and the detection rate of those larger than 1 cm was 92% (24/26).

Keyword

Liver, CT; Liver neoplasms, diagnosis; Compated tomography (CT), helical

MeSH Terms

Carcinoma, Hepatocellular*
Humans
Retrospective Studies
Tomography, Spiral Computed*
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