J Korean Soc Magn Reson Med.  2001 Dec;5(2):130-137.

Perfusion MR Imaging of Cerebral Gliomas: Comparison with Histologic Tumor Grade

Affiliations
  • 1Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Korea. cgchoi@www.amc.seoul.kr
  • 2Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Korea.
  • 3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Korea.

Abstract

PURPOSE: Our purpose was to compare maximum relative cerebral blood volume (rCBV) with histologic grade of cerebral gliomas.
MATERIALS AND METHODS
First-pass perfusion MR imaging was performed preoperatively in 16 patients with pathologically proven cerebral gliomas (7 glioblastoma, 2 anaplastic astrocytoma, 1 anaplastic oligo-dendroglioma, 5 low-grade astrocytoma, and 1 low-grade oligodendroglioma). Maximum rCBV was com-pared with histologic diagnosis and grade of the tumor.
RESULTS
Maximum rCBVs of glioblastomas were in the range of 433%-1330% (average, 790%), as compared with those of contra-lateral normal white matters. Maximum rCBVs of two non-enhancing anaplastic astrocytomas were 66% and 284%, respectively. Maximum rCBV of one well-enhancing anaplastic oligodendroglioma was 502%. Maximum rCBVs of low-grade astrocytomas were in the range of 80%-369% (average, 202%). Maximum rCBV of one low-grade oligodendroglioma was 1450%, even higher than those of glioblastomas.
CONCLUSION
Maximum rCBV was higher in glioblastoma than in low-grade astrocytoma without overlap-ping. However, there was no difference of maximum rCBV between non-enhancing anaplastic astrocytoma and low-grade astrocftoma.

Keyword

Brain, perfusion; Brain, MR; Brain, tumor

MeSH Terms

Astrocytoma
Blood Volume
Diagnosis
Glioblastoma
Glioma*
Humans
Magnetic Resonance Imaging*
Oligodendroglioma
Perfusion*
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