Korean J Cytopathol.  1999 Dec;10(2):151-155.

Bronchial Brushing and Bronchial Washing Cytologic Features of Primary Malignant Fibrous Histiocytoma of the Lung: A Case Report

• Park MO
• Ahn WS

Abstract

A case of primary malignant fibrous histiocytoma(MFH) of the lung occurring in a 62-year-old man is presented. After preoperative bronchial brushing and washing cytologic diagnosis of poorly differentiated carcinoma, surgical resection and lymph nodes dissection were performed. Subsequent histologic examination revealed a primary MFH. The diagnosis was confirmed by electron microscopic and immunohistochemical examinations. The review of the bronchial brushing and washing cytologic features disclosed many bipolar and a few unipolar spindle tumor cells with a "comet" configuration, mainly single cells, but also forming loose clusters. The nuclei were elongated and hyperchromatic and contained one or more irregular nucleoli. Scattered bizarre, multinucleated tumor giant cells were also present.

Keyword

Lung; Malignant fibrous histiocytoma; Bronchial brushing; Bronchial washing; Cytology

MeSH Terms

Diagnosis
Giant Cells
Histiocytoma, Malignant Fibrous*
Humans
Lung*
Lymph Nodes
Middle Aged