J Bacteriol Virol.  2013 Dec;43(4):307-316. 10.4167/jbv.2013.43.4.307.

Molecular Characterization of Norovirus and Rotavirus in Outbreak of Acute Gastroenteritis in Seoul

• Oh SA
• Park SH
• Ham HJ
• Seung HJ
• Jang JI
• Suh SW
• Jo SJ
• Choi SM
• Jeong HS

• KMID: 1501999
• DOI: http://doi.org/10.4167/jbv.2013.43.4.307

Abstract

Norovirus and rotavirus are important causes of acute nonbacterial gastroenteritis in communities worldwide. Genotypes of norovirus and rotavirus in stool samples, which were collected from patients, was determined by RT-PCR and ELISA. A total 4,484 stool samples (461 outbreak cases) collected during January 2010-April 2013 were analyzed. Four hundred thirty eight of samples were positive for norovirus. Twelve samples were positive for Rotavirus. Norovirus genotypes identified were nine kinds of G I genotype (G I -1, G I -2, G I -3, G I -4, G I -6, G I -7, G I -9, G I -12, G I -13) and nine kinds of G II genotype(G II -2, G II -4, G II -5, G II -6, G II -7, G II -11, G II -12, G II -15, G II -16). Rotavirus genotypes were G2P[4]. The results might be useful information for evaluating the epidemiological status of viral diarrhea in Seoul, and providing a strategy to prevent human norovirus, rotavirus and other threats to public health in Korea.

Keyword

Norovirus; Rotavirus; Genotypes; Gastroenteritis outbreak

MeSH Terms

Diarrhea
Enzyme-Linked Immunosorbent Assay
Gastroenteritis*
Genotype
Humans
Korea
Norovirus*
Public Health
Rotavirus*
Seoul*