J Vet Sci.  2013 Mar;14(1):85-90. 10.4142/jvs.2013.14.1.85.

Pulsed tissue Doppler imaging of the left ventricular septal mitral annulus in healthy dogs

• Choi J
• Kim H
• Yoon J

• KMID: 1482817
• DOI: http://doi.org/10.4142/jvs.2013.14.1.85

Abstract

This study evaluated pulsed TDI variables including the isovolumic time interval and duration of the major wave in a population of large healthy dogs. Longitudinal myocardial motion at the septal mitral annulus was evaluated with pulsed TDI in 45 healthy adult dogs. Maximal myocardial velocities, isovolumic time intervals, and duration of the myocardial waves were measured. The correlation between time intervals and velocity variables was also investigated. The mean maximal systolic velocity was 6.92 +/- 1.78 cm/sec, the mean early diastolic velocity (Em) was 6.58 +/- 1.81 cm/sec, the mean late diastolic velocity (Am) was 5.10 +/- 2.00 cm/sec, the mean isovolumic contraction time (IVCT) was 53.61 +/- 95.13 msec, and the mean isovolumic relaxation time (IVRT) was 26.74 +/- 57.24 msec. The early diastolic mitral inflow velocity (E)/Em ratio was 10.94 +/- 3.27 while the Em/Am ratio was 1.40 +/- 0.40. There was a negative correlation between Am duration and Am amplitude, and a positive correlation between the IVRT and Em/Am ratio (p < 0.05). The normal LV parameter using pulsed TDI method could be used as the reference range for identifying myocardial dysfunction in dogs.

Keyword

dog; longitudinal; pulsed; septal mitral annulus; tissue Doppler imaging

MeSH Terms

Animals
Dogs/*anatomy & histology
Female
Heart Ventricles/*ultrasonography
Male
Mitral Valve/*ultrasonography
Ultrasonography, Doppler, Pulsed/methods/*veterinary

Figure

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  Fig. 1 (A) The correlations between DurSm and myocardium systolic velocity of Sm, (B) between DurSm and fractional shortening (FS), (C) between IVCT and Sm, and (D) between IVCT and FS. No significant correlations were observed.

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  Fig. 2 (A) The correlations between DurEm with Em, and DurAm with Am (B). There was a negative correlation between DurAm and Am. Among the correlation (C) between IVRT and Am, (D) between IVRT and Em, and (E) between IVRT and Em/Am ratio, IVRT was positively correlated with the Em/Am ratio.

Reference

1. Bolognesi R, Tsialtas D, Barilli AL, Manca C, Zeppellini R, Javernaro A, Cucchini F. Detection of early abnormalities of left ventricular function by hemodynamic, echo-tissue Doppler imaging, and mitral Doppler flow techniques in patients with coronary artery disease and normal ejection fraction. J Am Soc Echocardiogr. 2001. 14:764–772.

2. Bruch C, Schmermund A, Bartel T, Schaar J, Erbel R. Tissue Doppler imaging: a new technique for assessment of pseudonormalization of the mitral inflow pattern. Echocardiography. 2000. 17(6 Pt 1):539–546.

3. Cannesson M, Jacques D, Pinsky MR, Gorcsan J 3rd. Effects of modulation of left ventricular contractile state and loading conditions on tissue Doppler myocardial performance index. Am J Physiol Heart Circ Physiol. 2006. 290:H1952–H1959.

4. Chetboul V, Blot S, Sampedrano CC, Thibaud JL, Granger N, Tissier R, Bruneval P, Gaschen F, Gouni V, Nicolle AP, Pouchelon JL. Tissue Doppler imaging for detection of radial and longitudinal myocardial dysfunction in a family of cats affected by dystrophin-deficient hypertrophic muscular dystrophy. J Vet Intern Med. 2006. 20:640–647.

5. Chetboul V, Carlos C, Blot S, Thibaud JL, Escriou C, Tissier R, Retortillo JL, Pouchelon JL. Tissue Doppler assessment of diastolic and systolic alterations of radial and longitudinal left ventricular motions in Golden Retrievers during the preclinical phase of cardiomyopathy associated with muscular dystrophy. Am J Vet Res. 2004. 65:1335–1341.

6. Chetboul V, Gouni V, Sampedrano CC, Tissier R, Serres F, Pouchelon JL. Assessment of regional systolic and diastolic myocardial function using tissue Doppler and strain imaging in dogs with dilated cardiomyopathy. J Vet Intern Med. 2007. 21:719–730.

7. Chetboul V, Sampedrano CC, Tissier R, Gouni V, Saponaro V, Nicolle AP, Pouchelon JL. Quantitative assessment of velocities of the annulus of the left atrioventricular valve and left ventricular free wall in healthy cats by use of two-dimensional color tissue Doppler imaging. Am J Vet Res. 2006. 67:250–258.

8. Disatian S, Bright JM, Boon J. The effects of age and heart rate on tricuspid annular motion velocities in healthy nonsedated cats. J Vet Intern Med. 2007. 21:731–736.

9. Giorgi D, Di Bello V, Pedrinelli R, Bertini A, Talini E, Dell'Omo G, Mengozzi G, Palagi C, Dell'Anna R, Mariani M. Ultrasonic tissue characterization and Doppler tissue imaging in the analysis of left ventricular function in essential arterial hypertension: a preliminary study. Echocardiography. 2002. 19:187–198.

10. Hansson K, Häggström J, Kvart C, Lord P. Left atrial to aortic root indices using two-dimensional and M-mode echocardiography in cavalier King Charles spaniels with and without left atrial enlargement. Vet Radiol Ultrasound. 2002. 43:568–575.

11. Ho CY, Solomon SD. A clinician's guide to tissue Doppler imaging. Circulation. 2006. 113:e396–e398.

12. Isaaz K, Thompson A, Ethevenot G, Cloez JL, Brembilla B, Pernot C. Doppler echocardiographic measurement of low velocity motion of the left ventricular posterior wall. Am J Cardiol. 1989. 64:66–75.

13. Koffas H, Dukes-McEwan J, Corcoran BM, Moran CM, French A, Sboros V, Simpson K, McDicken WN. Pulsed tissue Doppler imaging in normal cats and cats with hypertrophic cardiomyopathy. J Vet Intern Med. 2006. 20:65–77.

14. Nagueh SF, Lakkis NM, Middleton KJ, Spencer WH 3rd, Zoghbi WA, Quiñones MA. Doppler estimation of left ventricular filling pressures in patients with hypertrophic cardiomyopathy. Circulation. 1999. 99:254–261.

15. Nagueh SF, Mikati I, Kopelen HA, Middleton KJ, Quiñones MA, Zoghbi WA. Doppler estimation of left ventricular filling pressure in sinus tachycardia. A new application of tissue Doppler imaging. Circulation. 1998. 98:1644–1650.

16. Oki T, Tabata T, Mishiro Y, Yamada H, Abe M, Onose Y, Wakatsuki T, Iuchi A, Ito S. Pulsed tissue Doppler imaging of left ventricular systolic and diastolic wall motion velocities to evaluate differences between long and short axes in healthy subjects. J Am Soc Echocardiogr. 1999. 12:308–313.

17. Oki T, Tabata T, Yamada H, Wakatsuki T, Shinohara H, Nishikado A, Iuchi A, Fukuda N, Ito S. Clinical application of pulsed Doppler tissue imaging for assessing abnormal left ventricular relaxation. Am J Cardiol. 1997. 79:921–928.

18. O'Sullivan ML, O'Grady MR, Minors SL. Assessment of diastolic function by Doppler echocardiography in normal Doberman Pinschers and Doberman Pinschers with dilated cardiomyopathy. J Vet Intern Med. 2007. 21:81–91.

19. Oyama MA, Sisson DD, Bulmer BJ, Constable PD. Echocardiographic estimation of mean left atrial pressure in a canine model of acute mitral valve insufficiency. J Vet Intern Med. 2004. 18:667–672.

20. Sohn DW, Chai IH, Lee DJ, Kim HC, Kim HS, Oh BH, Lee MM, Park YB, Choi YS, Seo JD, Lee YW. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function. J Am Coll Cardiol. 1997. 30:474–480.

21. Teshima K, Asano K, Sasaki Y, Kato Y, Kutara K, Edamura K, Hasegawa A, Tanaka S. Assessment of left ventricular function using pulsed tissue Doppler imaging in healthy dogs and dogs with spontaneous mitral regurgitation. J Vet Med Sci. 2005. 67:1207–1215.

22. Vinereanu D, Khokhar A, Fraser AG. Reproducibility of pulsed wave tissue Doppler echocardiography. J Am Soc Echocardiogr. 1999. 12:492–499.

23. Wang M, Yip GWK, Wang AYM, Zhang Y, Ho PY, Tse MK, Lam PKW, Sanderson JE. Peak early diastolic mitral annulus velocity by tissue Doppler imaging adds independent and incremental prognostic value. J Am Coll Cardiol. 2003. 41:820–826.

24. Wess G, Killich M, Hartmann K. Comparison of pulsed wave and color Doppler myocardial velocity imaging in healthy dogs. J Vet Intern Med. 2010. 24:360–366.