J Korean Bone Joint Tumor Soc.  2011 Dec;17(2):95-99. 10.5292/jkbjts.2011.17.2.95.

Double Primary Presentation of Liposarcoma and Ewing's Sarcoma: A Case Report

• Park HW
• Jung ST
• Nah SY

• KMID: 1444796
• DOI: http://doi.org/10.5292/jkbjts.2011.17.2.95

Abstract

The development of different entities of soft tissue sarcoma in one patient is rare. It usually affects head and neck or abdominal region, whereas those affecting the extremities are much rarer. We describe a patient with double primary presentation of liposarcoma and Ewing's sarcoma in extremity. This case implies that sarcoma patients are at increased risk of a second malignancy, and this implies a need to search for occult tumors during follow up.

Keyword

liposarcoma; metachronous; Ewing's sarcoma; primitive neuroectodermal tumor

MeSH Terms

Extremities
Follow-Up Studies
Head
Humans
Liposarcoma
Neck
Neoplasms, Second Primary
Neuroectodermal Tumors, Primitive
Sarcoma
Sarcoma, Ewing

Figure

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  Figure 1. (A) Axial T2-weighted fat-saturated image, (B) Axial T1-weighted image, and (C) gadolinium enhancing image showing mass in proximal thigh.

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  Figure 2. Tc99-bone scans showing diffuse uptake left proximal thigh and no other site of disease. (A) Anteroposterior, and (B) posteroanterior bone scan view.

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  Figure 3. (A) A high-power photomicrograph of the specimen shows findings compatible with liposarcoma (Stain, hematoxylin & eosin; magnification, ×200) and (B) positive S-100 immunohistochemical analysis stain.

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  Figure 4. 2 years and 6 months follow up radiographs showing a new osteolytic lesion in proximal tibia. Anteroposterior (A) and lateral view (B).

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  Figure 5. Magnetic resonance imaging showing heterogenous enhancing mass. (A) proximal tibia and (B) left ilium.

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  Figure 6. Pathology revealing ES/PNET. (A) photomicrograph (Stain, hematoxylin & eosin; magnification, ×200), (B) CD56, (C) CD99, and (D) FLI-1 of immunohistochemical analysis.

Reference

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