J Korean Soc Radiol.  2011 Apr;64(4):297-301. 10.3348/jksr.2011.64.4.297.

Xanthomatous Hypophysitis: A Case Report and Literature Review

• Jang SJ
• Kim EJ
• Choi WS
• Park BJ

• KMID: 1443530
• DOI: http://doi.org/10.3348/jksr.2011.64.4.297

Abstract

Xanthomatous hypophysitis is a rare inflammatory disorder of the pituitary gland of unknown prevalence that causes pituitary dysfunction and a mass-like lesion. The authors report a case of 40-year-old man with a visual disturbance and a confirmed diagnosis of xanthomatous hypophysitis.

MeSH Terms

Adult
Humans
Magnetic Resonance Imaging
Pituitary Gland
Prevalence
Sella Turcica

Figure

• 

  Fig. 1 A-D. T1-weighted sagittal (A) and T2-weighted axial (B) images showing diffuse enlargement of the pituitary gland and a cystic portion (arrow) at the suprasellar area with high signal intensity. Gd-enhanced T1-weighted coronal (C) and sagittal (D) images showing homogenous enhancement of an enlarged pituitary gland.

• 

  Fig. 2 A. Photomicrograph showing xanthoma and multinucleated giant cells (Original magnification ×400). B. Immunostaining for CD68 was positive, indicating the presence of xanthoma cells and confirming xanthomatous hypophysitis.

Reference

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