Korean J Urol.  2008 Oct;49(10):917-922. 10.4111/kju.2008.49.10.917.

Treatment of Simple Renal Cysts by Percutaneous Aspiration and OK-432 Sclerotherapy

• Park SJ
• Ham WS
• Kim WT
• Lee DH
• Cho SY
• Cho KS
• Choi YD

• KMID: 1204322
• DOI: http://doi.org/10.4111/kju.2008.49.10.917

Abstract

PURPOSE: Percutaneous aspiration with sclerotherapy has been widely used for the treatment of symptomatic or large simple renal cysts. Ethanol has been most commonly used as a sclerosing agent; however, a temporary percutaneous nephrostomy for multiple ethanol injections is necessary to achieve a low recurrence rate. Thus, we used OK-432 as a new sclerosing agent without a temporary percutaneous nephrostomy for multiple injections, and also compared our results with the results of previous studies. MATERIALS AND METHDOS: Between October 2005 and April 2006, 50 patients (63 simple renal cysts) who underwent percutaneous OK-432 sclerotherapy for simple renal cysts were evaluated. The simple renal cysts were aspirated under ultrasonography and fluoroscopy, after which OK-432 was injected into the cyst. Follow-up was performed with ultrasonography or CT scan after 3 months. Regression of the renal cyst or a >70% reduction in size with no symptoms was considered a treatment success.
RESULTS
Among 63 renal cysts in 50 patients, complete regression occurred in 17(27.0%). Greater than a 90% reduction in size occurred in 8(12.7%), a 80-90% reduction in size occurred in 21(33.3%), and a 70-80% reduction in size occurred in 15(23.8%); a <70% reduction in size occurred in 2 (3%). The overall efficacies of success were 96.8%. After the procedure, there were only some minor complications, such as mild fever, local pain, and liver function test elevation that subsided with symptomatic treatment.
CONCLUSIONS
Percutaneous OK-432 sclerotherapy is simple, safe, and effective and can be an alternative first-line therapy of simple renal cysts.

Keyword

Renal cyst; OK-432; Sclerotherapy

MeSH Terms

Cysts

Figure

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  Fig. 1. (A) Bilateral simple renal cysts on the lower pole of the right kidney (3.8cm) and the upper pole of the left kidney (6.0cm) in a CT coronal view. (B) Collapsed previous renal cyst after bilateral OK-432 (PicibanilⓇ) sclerosing therapy in a CT coronal view.

Reference

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