J Korean Med Sci.  1995 Feb;10(1):31-35. 10.3346/jkms.1995.10.1.31.

Profound hypotension immediately following insertion of methyl methacrylate during bipolar endoprosthesis in a patient with long-term levodopa-treated paralysis agitans

Affiliations
  • 1Department of Anesthesiology, College of Medicine, Dongguk University, Pohang, Korea.

Abstract

Insertion of methyl methacrylate polymer into newly reamed bony cavities has sometimes resulted in profound hypotension, cardiac arrest, or sudden death which are more common in patients with hemodynamic instability or hypovolemia. In paralysis agitans(Parkinson's disease), dramatic worsening of the disease often occurs when another illness or trauma accompanies it. And it is possible that chronic medication with levodopa can cause the loss of ability to support blood pressure. So, it involves some risk to use methyl methacrylate in chronic levodopa-treated paralysis agitans. We present a case of paralysis agitans who demonstrated profound hypotension immediately following insertion of methyl methacrylate polymer in spite of normovolemia and proper anesthetic management.


MeSH Terms

Aged
Case Report
Hip Prosthesis/adverse effects
Human
Hypotension/*etiology
Levodopa/therapeutic use
Male
Methylmethacrylate
Methylmethacrylates/*adverse effects
Parkinson Disease/*drug therapy
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