Yonsei Med J.  1990 Mar;31(1):74-79. 10.3349/ymj.1990.31.1.74.

Locally advanced unresectable gastric cancer successfully resected after neoadjuvant chemotherapy with FADE regimen

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of General Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 4Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The prognosis of unresectable advanced gastric cancer is extremely poor. We tried a neoadjuvant chemotherapy in locally advanced unresectable stomach cancer diagnosed by initial explo-laparotomy. After chemotherapy with the FADE regimen (5-fluorouracil + adriamycin + cisplatin + etoposide), the patient was diagnosed clinically as a complete response state on re-staging with radiological gastrointestinal study, fiber-gastroscopy and computerized tomography. During the second-look operation, the advanced cancer was completely resected and the pathological diagnosis was early gastric cancer (EGC) type IIc, stage II (T1N2Mo).

Keyword

Neoadjuvant chemotherapy; FADE regimen

MeSH Terms

Adenocarcinoma/*drug therapy/radiography
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Case Report
Cisplatin/*administration & dosage
Combined Modality Therapy
Doxorubicin/*administration & dosage
Etoposide/*administration & dosage
Fluorouracil/*administration & dosage
Human
Male
Middle Age
Stomach/pathology/radiography
Stomach Neoplasms/drug therapy/radiography/*surgery
Tomography, X-Ray Computed
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