Yonsei Med J.  1991 Jun;32(2):190-194. 10.3349/ymj.1991.32.2.190.

A case of HTLV-I associated myelopathy(HAM) in Korea

Affiliations
  • 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Rehabilitation, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine3, Facuity of Medicine, Kogoshima University, Kagoshima, Japan.

Abstract

We report the first Korean case of HTLV-I associated myelopathy (HAM), which was confirmed by Western blot assay of serum and cerebrospinal fluid. Interestingly, the proband's wife was a Japanese Korean who had lived in the endemic area of HAM, Kyushu. Japan, Investigations revealed significantly elevated anti HTLV-I antibody titers in the serum, but not in the CSF, suggesting that she was a carrier of HTLV-I. Considering that the patient had not had a previous blood transfusion, the most common route of HTLV-I, it is likely that the patient was infected by his wife through sexual intercourse. Although previous reports suggest that the transmission of HTLV-I is essentially from man to man or man to woman, our case suggests that woman to man transmission also occurs.

Keyword

HTLV-1; Myelopathy; TSP

MeSH Terms

Adult
Blotting, Western
HTLV-I Antibodies/analysis
Human
Korea/epidemiology
Male
Paraparesis, Tropical Spastic/*epidemiology/immunology
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