Yonsei Med J.  2010 May;51(3):326-331. 10.3349/ymj.2010.51.3.326.

Surgical Management of Coexisting Coronary Artery and Valvular Heart Disease

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea. kjy@yuhs.ac

Abstract

PURPOSE
Combined coronary artery bypass (CAB) and valve surgery is one of the most challenging surgical procedures, but the operative results have improved over the years.
MATERIALS AND METHODS
From 1989 through 2004, combined CAB and valve operations were performed in 125 patients. Mean age was 63 years, and 86 patients were male. Forty-six patients were diagnosed with coronary artery disease during preoperative evaluation for valvular heart disease (VHD). All patients underwent CAB, and one or more underwent valve replacement or repair (mitral: 54, aortic: 61, tricuspid: 3, DVR: 7) simultaneously.
RESULTS
Mean number of distal graft was 1.98 +/- 1.07, and LIMA was used in 68% of patients. Early mortality occurred in 6 patients (4.8%), and the causes were heart failure (4) and sepsis (2). Mean follow-up duration was 91.4 +/- 40.9 months (range: 47-245), and late mortality occurred in 4 patients. Kaplan Meier estimated survival rates at 1, 5, and 10 years were 94.4%, 92.3%, and 89.9%, respectively.
CONCLUSION
Combined coronary and valve operations can be performed safely with optimal surgical results. Although the surgical mortality of coexisting coronary and VHD is higher than either isolated coronary or valvular operations, it may not affect the long-term survival.

Keyword

Coronary artery disease; coronary artery bypass; valvular diseases

MeSH Terms

Adult
Age Factors
Aged
Coronary Artery Bypass/*methods
Coronary Artery Disease/mortality/*surgery
Coronary Vessels/pathology/surgery
Female
Heart Valve Diseases/mortality/*surgery
Humans
Kaplan-Meiers Estimate
Male
Middle Aged
Sex Factors
Treatment Outcome

Figure

  • Fig. 1 Age distribution of coronary artery disease in male patients.

  • Fig. 2 Age distribution of coronary artery disease in female patients.


Cited by  1 articles

Comparison of Early Clinical Outcomes Following Transcatheter Aortic Valve Implantation versus Surgical Aortic Valve Replacement versus Optimal Medical Therapy in Patients Older than 80 Years with Symptomatic Severe Aortic Stenosis
Eui Im, Myeong-Ki Hong, Young-Guk Ko, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Donghoon Choi, Chi Young Shim, Hyuk-Jae Chang, Jae-Kwang Shim, Young-Lan Kwak, Sak Lee, Byung-Chul Chang, Yangsoo Jang
Yonsei Med J. 2013;54(3):596-602.    doi: 10.3349/ymj.2013.54.3.596.


Reference

1. He GW, Grunkemeier GL, Starr A. Aortic valve replacement in elderly patients: Influence of concomitant coronary grafting on late survival. Ann Thorac Surg. 1996. 61:1746–1751.
2. DiSesa VJ, Cohn LH, Collins JJ Jr, Koster JK Jr, VanDevanter S. Determinants of operative survival following combined mitral valve replacement and coronary revascularization. Ann Thorac Surg. 1982. 34:482–489.
Article
3. Czer LS, Gray RJ, DeRobertis MA, Bateman TM, Stewart ME, Chaux A, et al. Mitral valve replacement: impact of coronary artery disease and determinants of prognosis after revascularization. Circulation. 1984. 70:I198–I207.
4. Lytle BW, Cosgrove DM, Gill CC, Stewart RW, Golding LA, Goormastic M, et al. Mitral valve replacement combined with myocardial revascularization: early and late results for 300 patients, 1970 to 1983. Circulation. 1985. 71:1179–1190.
Article
5. Kirklin JK, Naftel DC, Blackstone EH, Kirklin JW, Brown RC. Risk factors for mortality after primary combined valvular and coronary artery surgery. Circulation. 1989. 79:I185–I190.
6. Ferguson TB Jr, Dziuban SW Jr, Edwards FH, Eiken MC, Shroyer AL, Pairolero PC, et al. The STS National Database: current changes and challenges for the new millennium. Committee to Establish a National Database in Candiothoracic Surgery, The Society of Thoracic Surgeons. Ann Thorac Surg. 2000. 69:680–691.
Article
7. Minale C, Messmer BJ. Combination of mitral and coronary artery surgery. J Cardiovasc Surg (Torino). 1986. 27:480–487.
8. Ashraf SS, Shaukat N, Odom N, Keenan D, Grotte G. Early and late results following combined coronary bypass surgery and mitral valve replacement. Eur J Cardiothorac Surg. 1994. 8:57–62.
Article
9. He GW, Hughes CF, McCaughan B, Thomson DS, Leckie BD, Yang CQ, et al. Mitral valve replacement combined with coronary artery operation: determinants of early and late results. Ann Thorac Surg. 1991. 51:916–922.
Article
10. Herlitz J, Brandrup-Wognsen G, Caidahl K, Haglid M, Karlsson BW, Karlsson T, et al. Mortality and morbidity among patients who undergo combined valve and coronary artery bypass surgery: early and late results. Eur J Cardiothorac Surg. 1997. 12:836–846.
Article
11. National adult cardiac surgical database report, 2000-2001. The Society for Cardiothoracic Surgery in Great Britain and Ireland. 2002. October. http://www.scts.org/sections/audit/cardiac/index.html.
12. Karthik S, Srinivasan AK, Grayson AD, Jackson M, Sharpe DA, Keenan DJ, et al. Limitations of additive EuroSCORE for measuring risk stratified mortality in combined coronary and valve surgery. Eur J Cardiothorac Surg. 2004. 26:318–322.
13. Bonow RO, Carabello BA, Chatterjee K, de Leon AC Jr, Faxon DP, Freed MD, et al. American College of Cardiology, American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1998 guidelines for the management of patients with valvular heart disease). Society of Cardiovascular Anesthesiologists. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing Committee to Revise the 1998 guidelines for the management of patients with valvular heart disease) developed in collaboration with the Society of Cardiovascular Anesthesiologists endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2006. 48:e1–e148.
14. Choudhury L, Marsh JD. Myocardial infarction in young patients. Am J Med. 1999. 107:254–261.
Article
15. Zimmerman F, Cameron A, Fisher LD, Ng G. Myocardial infarction in young adults: angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Study Registry). J Am Coll Cardiol. 1995. 26:654–661.
Article
16. Doughty M, Mehta R, Bruckman D, Das S, Karavite D, Tsai T, et al. Acute myocardial infarction in the young--The University of Michigan experience. Am Heart J. 2002. 143:56–62.
Article
17. Barbash GI, White HD, Modan M, Diaz R, Hampton JR, Heikkila J, et al. Acute myocardial infarction in the young--the role of smoking. The Investigators of the International Tissue Plasminogen Activator/Streptokinase Mortality Trial. Eur Heart J. 1995. 16:313–316.
18. Fournier JA, Cabezón S, Cayuela A, Ballesteros SM, Cortacero JA, Díaz De La Llera LS. Long-term prognosis of patients having acute myocardial infarction when </=40 years of age. Am J Cardiol. 2004. 94:989–992.
Article
19. Ohnesorge BM, Hofmann LK, Flohr TG, Schoepf UJ. CT for imaging coronary artery disease: defining the paradigm for its application. Int J Cardiovasc Imaging. 2005. 21:85–104.
Article
20. Yoo KJ, Choi D, Choi BW, Lim SH, Chang BC. The comparison of the graft patency after coronary artery bypass grafting using coronary angiography and multi-slice computed tomography. Eur J Cardiothorac Surg. 2003. 24:86–91.
Article
21. Emery RW, Erickson CA, Arom KV, Northrup WF 3rd, Kersten TE, Von Rueden TJ, et al. Replacement of the aortic valve in patients under 50 years of age: long-term follow-up of the St. Jude Medical prosthesis. Ann Thorac Surg. 2003. 75:1815–1819.
22. Berrebi AJ, Carpentier SM, Phan KP, Nguyen VP, Chauvaud SM, Carpentier A. Results of up to 9 years of high-temperature-fixed valvular bioprostheses in a young population. Ann Thorac Surg. 2001. 71:S353–S355.
23. Ruel M, Kulik A, Lam BK, Rubens FD, Hendry PJ, Masters RG, et al. Long-term outcomes of valve replacement with modern prostheses in young adults. Eur J Cardiothorac Surg. 2005. 27:425–433.
Article
24. Gao G, Wu Y, Grunkemeier GL, Furnary AP, Starr A. Long-term survival of patients after coronary artery bypass graft surgery: comparison of the pre-stent and post-stent eras. Ann Thorac Surg. 2006. 82:806–810.
25. El-Hamamsy I, Cartier R, Demers P, Bouchard D, Pellerin M. Long-term results after systematic off-pump coronary artery bypass graft surgery in 1000 consecutive patients. Circulation. 2006. 114:I486–I491.
Article
26. van Domburg RT, Kappetein AP, Bogers AJ. The clinical outcome after coronary bypass surgery: a 30-year follow-up study. Eur Heart J. 2009. 30:453–458.
Article
Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr