Korean J Ophthalmol.  2008 Sep;22(3):187-189. 10.3341/kjo.2008.22.3.187.

A Case of Diode Laser Photocoagulation in the Treatment of Choroidal Metastasis of Breast Carcinoma

• Lee SJ
• Kim SY
• Kim SD

• KMID: 1070756
• DOI: http://doi.org/10.3341/kjo.2008.22.3.187

Abstract

To report a single case of improvement on choroidal metastasis of breast cancer after laser photocoagulation. A 52-year-old female patient who complained of visual disturbance of the right eye with multiple states of metastasis of breast carcinoma. On initial examination, the right best-corrected visual acuity was 0.63. Right fundoscopy revealed an elevated mass-like lesion temporal to the macule with serous retinal detachment. The mass had a 3.5-disc diameter. A right fluorescein angiogram revealed hypofluorescence during the prearterial and arteriovenous phase and hyperfluorescence during the venous phase. The venous phase showed almost total masking of background choroidal fluorescence at the elevated lesion because of leakage and neovascularization. The patient was treated 4 times by diode laser photocoagulation in addition to chemotherapy. Fifty days after the diode laser treatments, the funduscopy examination and fluorescein angiogram revealed that the serous retinal detachment had been absorbed, the choroid had become flat, the lesion had been reduced in size and hyperfluorescence. The right best-corrected visual acuity was improved to 0.8. Laser photocoagulation appears not to cause any problems for the patient and may be an efficient treatment for patients with choroidal breast carcinoma.

Keyword

Breast carcinoma; Intraocular metastatic tumor; Laser therapy

MeSH Terms

Breast Neoplasms/pathology/*surgery
Carcinoma, Ductal, Breast/secondary/*surgery
Choroid Neoplasms/secondary/*surgery
Female
Fluorescein Angiography
Humans
Laser Coagulation/*methods
Lasers, Semiconductor/*therapeutic use
Middle Aged
Visual Acuity

Figure

• 

  Fig. 1 (A) Right fundoscopy revealed an elevated mass-like lesion temporal to the macule with serous retinal detachment. The mass had a 3.5-disc diameter. (B) A right fluorescein angiogram revealed hypofluorescence during the prearterial and arteriovenous phase and hyperfluorescence during the venous phase. (C) A right fluorescein angiogram revealed hypofluorescence duringthe venous phase showing a nearly complete masking of background choroidal fluorescence at the elevated lesion due to leakage and neovascularization.

• 

  Fig. 2 After 50 days, (A) Right fundoscopy revealed mass regression in size and height and resolved retinal detachment. (B, C) A right fluorescein angiogram revealed flat devascularized choroids. The venous phase showed leakages from the old lesion that affected the fovea

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