Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

33 results
Display

Historical Review and Future of Cardiac Xenotransplantation

Koh J, Chee HK, Kim KH, Jeong IS, Kim JS, Lee CH, Seo JW

Along with the development of immunosuppressive drugs, major advances on xenotransplantation were achieved by understanding the immunobiology of xenograft rejection. Most importantly, three predominant carbohydrate antigens on porcine endothelial cells...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Macrophages in xenotransplantation

Kim JY

Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Intra-articular Xenotransplantation of Adipose-Derived Stromal Cells to Treat Osteoarthritis in a Goat Model

Ko JY, Lee J, Lee J, Im GI

Adipose-derived stromal cells (ASCs) have been investigated as a cell source for tissue regeneration. The purpose of this study was first to confirm if medial meniscectomy induces osteoarthritis (OA) in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Current Status of Solid Organ Xenotransplantation

Yun IJ

Solid organ xenotransplantation using transgenic pig organs is proposed as an alternative method for allo-transplantation. To accomplish this, immunologic and non-immunologic barriers for xenotransplantation should be overcome, and experiments on...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Implications of Calcineurin/NFAT Inhibitors' Regulation of Dendritic Cells and Innate Immune Cells in Islet Xenotransplantation

Kim YH, Lee WW, Park CG

Calcineurin inhibitors, such as cyclosporine and tacrolimus (FK506) are broadly used in organ transplantations as immune suppressants. As the calcineurin/NFAT signaling pathway has been identified as critical pathway in the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Increase in Anti-Gal IgM Level is Associated With Early Graft Failure in Intraportal Porcine Islet Xenotransplantation

Kang HJ, Lee H, Park EM, Kim JM, Shin JS, Kim JS, Park CG, Kim SJ

BACKGROUND: Anti-Gal is a major antibody induced in non-human primates (NHPs) after xenotransplantation. To understand the mechanism of graft rejection, we investigated the association between anti-Gal responses and graft failure...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Evaluation of biocompatibility of alpha-1,3 galactosyltransferase knockout pig bone graft in a rat calvarial defect model

Kim SE, Choi GH, Shim KM, Choi SH, Lee SM, Kang SS

  • KMID: 1709210
  • J Biomed Res.
  • 2014 Jun;15(2):86-91.
The current study was conducted to evaluate the biocompatibility of alpha-1,3 galactosyltransferase knockout pig bone graft in a rat calvarial defect model. Porcine cancellous bones were harvested from general and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation

Hwang S, Jung YD, Cho K, Ock SA, Oh KB, Kim HS, Yun IJ, Ahn C, Park JK, Im S

This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organ-recipient monkeys that...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Analysis of env Subtypes of Porcine Endogenous Retrovirus in SNU Miniature Pigs

Sa M, Park CG, Hwang ES

All xenografts from pigs impose infection risk by porcine endogenous retrovirus (PERV). The purpose of this study was to investigate the env constructs with the comparison of the ratio of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Application of the Multiplex Cytokine Analysis to Monitor Xenogeneic Immune Responses to the Porcine Islet Graft in Non-Human Primate

Kim YH, Kim JS, Yoon IH, Shin JS, Kim JM, Kim SJ, Park CG

Non-human primate studies must be conducted prior to the clinical trial of xenotransplantation. In order to develop clinically applicable immune-modulatory regimen through non-human primate studies, close monitoring of xenogeneic immune...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Proteomic analysis of liver in miniature pigs according to developmental stages using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry

Yi SS, Oh SJ, Kim IY, Yeom HJ, Yeom SC, Hwang SY, Seong JK

  • KMID: 2312109
  • Lab Anim Res.
  • 2013 Sep;29(3):162-167.
Due to the shortage of human organ donors for transplant, various studies of xenotransplantation, or the use of animal organs instead of human organs, have been carried out. The organs...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Multidetector computed tomographic angiography evaluation of micropig major systemic vessels for xenotransplantation

Ryu JM, Yoon W, Park JH, Yun SP, Jang MW, Han HJ

Due primarily to the increasing shortage of allogeneic donor organs, xenotransplantation has become the focus of a growing field of research. Currently, micropigs are the most suitable donor animal for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Evaluation of Porcine Pancreatic Islets Transplanted in the Kidney Capsules of Diabetic Mice Using a Clinically Approved Superparamagnetic Iron Oxide (SPIO) and a 1.5T MR Scanner

Kim HS, Kim H, Park KS, Moon WK

OBJECTIVE: To evaluate transplanted porcine pancreatic islets in the kidney capsules of diabetic mice using a clinically approved superparamagnetic iron oxide (SPIO) and a 1.5T MR scanner. MATERIALS AND METHODS:...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
No Evidence of the Productive Replication of Porcine Endogenous Retrovirus (PERV) from SNU Miniature Pigs in Human Cell Line

Kim JH, Jung ES, Park CG, Kim SJ, Hwang ES

BACKGROUND: The presence of porcine endogenous retrovirus (PERV) has been considered as one of the main hurdles to transplant pig's organs or tissues to human beings. There has been no...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Current Strategies for Successful Islet Xenotransplantation

Kim H, Yang J, Ahn C

Diabetes mellitus is increasing all over the world and is a serious health problem. Pancreatic islet transplantation is promising treatment for diabetes mellitus, but an imbalance between deceased pancreas donors...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Current Status and Future Perspectives of Xenotransplantation

Park CG, Kim JS, Shin JS, Kim YH, Kim SJ

Xenotransplantation using pigs as the transplant source holds great promise to resolve the severe shortage of human organ donors. Although stem-cell-derived organ and tissue regeneration have a potential to solve...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Construction of the Porcine Endogenous Retrovirus Envelope Glycoprotein A and B Specific Antibody

Lee JE, Kim GW, Kim YB, Park HY

Xenotransplantation using porcine organs could potentially associate with the risk of pathogenic infections, because human tropic porcine endogenous retrovirus (PERV) particles could be released from pig cells or organs. While...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors

Ryu JM, Kim DH, Lee MY, Lee SH, Park JH, Yun SP, Jang MW, Kim SH, Rho GJ, Han HJ

The shortage of organ donors has stimulated interest in the possibility of using animal organs for transplantation into humans. In addition, pigs are now considered to be the most likely...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Characterization of Clones of Human Cell Line Infected with Porcine Endogenous Retrovirus (PERV) from Porcine Cell Line, PK-15

Kim JH, Choi EY, Jung ES, Kwon Y, Lee DS, Hwang DY, Hwang ES

BACKGROUND: Porcine endogenous retroviruses (PERVs) form part of the chromosomes of all pigs. Since they can be produced as infectious virion and infect human cells, safety issues on PERVs infection...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Current Status and Future Perspectives of Xenotransplantation and Stem Cell Research in Transplantation Field

Park CG, Kim JS, Kim YH

The severe shortage of human organ donors is one of the biggest problems with organ transplantation. The solution for this problem would be development of artificial organs or mechanical devices,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr