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Evaluation of Five User-Friendly Whole Genome Sequencing Software for Mycobacterium tuberculosis in Clinical Application

Kim N, Seok KH, Shin S, Kim B, Park H, Roh EY, Yoon JH, Shin S

Background: Whole genome sequencing (WGS) is an increasingly useful tool for tuberculosis (TB) diagnosis and disease management. In this study, we evaluated the utility of userfriendly WGS tools in reporting...
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Development of the SIKRIBO Mobile Health Application for Active Tuberculosis Case Detection in Semarang, Indonesia

Rahayu SR, Zainafree I, Merzistya ANA, Cahyati WH, Farida E, Wandastuti AD, I, Wahidah N, Saefurrohim MZ, Islam MAN, Fajri A, Subagja M

Objectives: This study was conducted to document the development and usability testing of SIKRIBO, a tuberculosis screening application. Methods: The SIKRIBO application was developed using design science research methodology, which has...
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Isolated Tuberculous Myositis: A Systematic Review and Multicenter Cases

Kim JH, Lee JS, Choi BY, Cheon YH, Yoo SJ, Ju JH, Shin K, Kim ES, Baek HJ, Park W, Song YW, Hong WH, Lee YJ

Objective: To investigate the clinical features and associated underlying conditions of isolated tuberculous myositis (ITBM), a rare extrapulmonary tuberculosis (TB). Methods: A systematic literature search and a multicenter survey were performed...
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Is 6 Months of Antitubercular Chemotherapy as Effective as More Than 6 Months Regimen in Spinal Tuberculosis? A Systematic Review and Meta-analysis

Aryal A, Garg B, Mehta N, Shekhar S, Gupta V

Historically, osteoarticular tuberculosis (TB), including spinal TB, was treated with prolonged course of antitubercular therapy (ATT). Due to various challenges, there has been reluctance to explore the use of short-course...
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Social Contact Patterns Associated With Tuberculosis: A Case-control Study in Southwest Iran

Amoori N, Cheraghian B, Amini P, Mohammad Alavi S

Objectives: Tuberculosis (TB) is a major public health concern worldwide. Social contact patterns can affect the epidemiology and risk of airborne diseases such as TB. This study was designed to...
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Management and 2 Years Follow-Up of Newborns in the Neonatal Intensive Care Unit Exposed to Congenital Tuberculosis

Yang JH, Lee JS, Song ES

Objective: We report the management and 2 years follow-up of newborns in the neonatal intensive care unit (NICU) exposed to congenital tuberculosis (Tb). Methods: Preterm twins born to a mother diagnosed...
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Knowledge and Attitudes of Indonesian General Practitioners Towards the Isoniazid Preventive Therapy Program in Indonesia

Winardi W, Yudistira Nalapraya W, Sarifuddin S, Anwar S, Yufika A, Wibowo A, Fadhil I, Wahyuni MS H, Arliny Y, Behtri Yanifitri D, Zulfikar T, Harapan H

Objectives: The Indonesian Ministry of Health launched isoniazid preventive therapy (IPT) in 2016, with general practitioners (GPs) at the frontline of this program. However, the extent to which GPs have...
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Fatal Pneumonia Caused by Omicron Subvariant BA.2 of Severe Acute Respiratory Syndrome Coronavirus 2 with the Pulmonary Tuberculosis

Heo JH, Park YI, Ko YS, Song HS, Ham SH, Kwon H, Na JY

The coronavirus disease 2019 (COVID-19) pandemic resulted from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Variants of SARSCoV-2 have caused distinct COVID-19 surges worldwide. The Omicron variant has replaced other...
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Latent and Active Tuberculosis Infection in Patients with Inflammatory Bowel Disease

Jin BC, Moon HJ, Kim SW

Latent tuberculosis (TB) infections (LTBI) impose clinical challenges in terms of the diagnosis and treatment of inflammatory bowel disease (IBD), especially in TB-endemic areas. While steroids and biologics have become...
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Susceptibility of β-Lactam Antibiotics and Genetic Mutation of Drug-Resistant Mycobacterium tuberculosis Isolates in Korea

Park S, Jung J, Kim J, Han SB, Ryoo S

Background Mycobacterium tuberculosis (Mtb) is resistant to the β-lactam antibiotics due to a non-classical transpeptidase in the cell wall with β-lactamase activity. A recent study showed that meropenem combined with...
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A Case Report of Isoniazid Induced Encephalopathy

Cho K, Hwang K

A 61-year-old male without a prior neurologic history presented with disturbances in consciousness and seizure that were suspected as related to the treatment of tuberculosis with isoniazid. The neurologic symptoms...
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Conceptual Analysis of Health Behavior in Tuberculosis Patients

Kim HJ, Lee MK

Purpose: Health behavior is important for the treatment of tuberculosis patients. This study aims to clarify the concept of health behavior in tuberculosis patients. Methods: We used Rodger's evolutionary concept analysis...
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Total elbow arthroplasty for active primary tuberculosis of the elbow: a curious case of misdiagnosis

Pattu R, Chellamuthu G, Sellappan K, Chendrayan K

The incidence of musculoskeletal tuberculosis (TB) is on the rise due to the current Acquired Immunodeficiency Syndrome (AIDS) pandemic. Spine is the most common osseous site, followed by other joints....
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A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis

Song S, Zhang Q, Yang H, Guo J, Xu M, Yang N, Yi J, Wang Z, Chen C

Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components...
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Cohort Profile: Korean Tuberculosis and Post-Tuberculosis Cohort Constructed by Linking the Korean National Tuberculosis Surveillance System and National Health Information Database

Jeong D, Kang HY, Kim J, Lee H, Yoo BN, Kim HS, Choi H

We aimed to review the current data composition of the Korean Tuberculosis and Post-Tuberculosis Cohort, which was constructed by linking the Korean Tuberculosis Surveillance System (KNTSS; established and operated by...
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Four months of rifampicin monotherapy for latent tuberculosis infection in children

Oh CE, Menzies D

Diagnosing and treating latent tuberculosis infection (LTBI) is an important part of efforts to combat tuberculosis (TB). The Korean guidelines for TB published in 2020 recommend 2 LTBI regimens for...
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Analysis of Adverse Drug Reactions to First-Line Anti-Tuberculosis Drugs Using the Korea Adverse Event Reporting System

Chung SJ, Byeon Sj, Choi JH

Background: Adverse drug reactions (ADRs) to first-line anti-tuberculosis (TB) drugs are common; however, there have been few reports of nationwide epidemiologic studies on ADRs to anti-TB drugs in Korea. This...
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Differential Diagnosis of Inflammatory Arthropathy Accompanying Active Tuberculosis Infection

Jung Y, Choi BY

Objective: The study aimed to ascertain the clinical manifestations of inflammatory arthritis accompanying tuberculosis (TB) for the differential diagnosis. Methods: We retrospectively reviewed patients with active TB who presented with inflammatory...
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The Risk of Tuberculosis in Patients With Inflammatory Bowel Disease Treated With Vedolizumab or Ustekinumab in Korea

Choi MG, Ye BD, Yang SK, Shim TS, Jo KW, Park SH

The present study investigated the risk of active tuberculosis in patients with inflammatory bowel disease (IBD) treated with vedolizumab or ustekinumab, in actual clinical settings in a country with an...
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A Case of Nasopharyngeal Tuberculosis Which Was Difficult to Differentiate From Sarcoidosis

Jang DH, Kim HC, Hong YO, Kim JS

Nasopharyngeal mass is a disease that can cause unilateral or bilateral nasal obstruction. Common diseases that can cause nasal obstruction include antrochoanal polyp, adenoid remnants, juvenile nasopharyngeal angiofibroma, and nasopharyngeal...
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