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Elevated interleukin-10 levels in patients with ocular toxoplasmosis

Kim GH, Kwak JH, Park YH

In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults....
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Delayed Cerebral Toxoplasmosis in a Kidney Transplant Patient: a Case Report

Myeong H, Park M, Kim JE, Park SW, Lee SH

Cerebral toxoplasmosis is often life-threatening in an immunocompromised patient due to delayed diagnosis and treatment. Several differential diagnoses could be possible only with preoperative brain images of cerebral toxoplasmosis which...
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Recurrent Toxoplasma Retinitis Treated with Long-Term Oral Antibiotics

Yeom H, Park SH, Cho H, Shin YU

Purpose: The purpose of this case was to report the inhibition of toxoplasma retinitis reactivation with long-term, low-dose antibiotics. Case summary: A 76-year-old woman complained of poor vision and floaters in...
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Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea

Yu J, Kim W, Chang YK, Kim TS, Hong SJ, Ahn HJ, Nam HW, Kim D

We find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in Gyodong-myeon and Samsan-myeon of Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea. Seroepidemiological data of toxoplasmosis surveyed using...
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Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea

Jung J, Lee J, Chang YK, Ahn SK, Park SH, Hong SJ, Lee J, Chong CK, Ahn HJ, Nam HW, Kim TS, Kim D

Toxoplasma gondii seroprevalence have been rapidly increasing in some parts of Korea. We analyzed prevalence of anti-Toxoplasma gondii antibodies, using a rapid diagnostic test (RDT), in the sera of 552...
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Bilateral Ocular Toxoplasmosis that Caused Optic Atrophy Secondary to Papillitis

Lee D, Kim M, Moon JW

Purpose: We report a case of ocular toxoplasmosis that caused bilateral optic atrophy secondary to papillitis. Case summary: A 52-year-old male with no history of systemic disease was referred to our...
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4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages

lee J, Choi JW, Han HY, Kim WS, Song HY, Byun EB, Byun EH, Lee YH, Yuk JM

Toxoplasma gondii is an intracellular protozoan parasite that infects approximately one third of the human popu- lation worldwide. Considering the toxicity and side effects of anti-toxoplasma medications, it is important...
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Primary Ocular Toxoplasmosis Presenting to Uveitis Services in a Non-endemic Setting

Bhikoo R, Damato EM, Guest S, Sims J

PURPOSE: This study sought to describe the different clinical features and presentations of primary ocular toxoplasmosis in a setting not demonstrating an outbreak of disease. METHODS: This was a retrospective review...
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Fulminant Toxoplasmic Chorioretinitis Following Intravitreal Dexamethasone Implantation

Jeong A, Park DG, Sagong M

PURPOSE: To report a case of fulminant toxoplasmic chorioretinitis following intravitreal dexamethasone implantation monotherapy in a stabilized toxoplasmic chorioretinitis patient with initial treatment. CASE SUMMARY: A 60-year-old healthy female presented with...
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Congenital toxoplasmosis among Iranian neonates: a systematic review and meta-analysis

Sarvi S, Nayeri Chegeni T, Sharif M, Montazeri , Hosseini S, Amouei A, Hosseininejad Z, Anvari D, Saberi R, Gohardehi , Daryani A

Toxoplasmosis is a serious zoonotic disease that can lead to abortion and congenital disorders and has a widespread global distribution in humans and animals. The objective of this review was...
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Serologic Tests of IgG and IgM Antibodies and IgG Avidity for Diagnosis of Ocular Toxoplasmosis

Rahimi-Esboei B, Zarei M, Mohebali M, Valian HK, Shojaee S, Mahmoudzadeh R, Salabati M

This prospective study was aimed to detect acute and chronic ocular toxoplasmosis by comparison of anti-Toxoplasma gondii IgM and IgG antibody levels and IgG avidity test. One hundred and seventeen...
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Isolation and Genotyping of Toxoplasma gondii in Brazilian Dogs

da Silva J, Maciel BM, de Santana Souza Santos LKN, Carvalho F, de Santana Rocha D, Lopes CW, Albuquerque GR

Strains of Toxoplasma gondii in Brazil are highly genetically diverse compared to strains from North America and Europe. Dogs are epidemiologically important because they act as sentinels for T. gondii...
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Toxoplasmic Encephalitis in Patient with Acquired Immunodeficiency Syndrome

Lee SB, Lee TG

Toxoplasmic encephalitis (TE) is an opportunistic infection found in immunocompromised patients and TE related cerebral mass lesion is often reported in acquired immunodeficiency acquired immunodeficiency syndrome (AIDS) patients. However, incidence...
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Ocular Inflammation Associated with Systemic Infection

Moon BG, Lee JY

Systemic infections that are caused by various types of pathogenic organisms can be spread to the eyes as well as to other solid organs. Bacteria, parasites, and viruses can invade...
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Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Toxoplasma gondii Apical Membrane Antigen 1 (AMA1)

Vetrivel U, Muralikumar S, Mahalakshmi B, Lily Therese K, Madhavan H, Alameen M, Thirumudi

Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by...
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Chronic Toxoplasmosis Modulates the Induction of Contact Hypersensitivity by TNCB in Mouse Model

Yang Z, Ahn HJ, Nam HW

Mouse models of chronic toxoplasmosis and atopic dermatitis (AD) were combined to clarify the effect of opportunistic Toxoplasma gondii infection on the development of AD. AD was induced as a...
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Toxoplasmosis in a Pet Peach-Faced Lovebird (Agapornis roseicollis)

Cooper MK, Slapeta J, Donahoe SL, Phalen DN

Toxoplasma gondii atypical type II genotype was diagnosed in a pet peach-faced lovebird (Agapornis roseicollis) based on histopathology, immunohistochemistry, and multilocus DNA typing. The bird presented with severe neurological signs,...
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Seropositivity of Toxoplasmosis in Pregnant Women by ELISA at Minia University Hospital, Egypt

Kamal AM, Ahmed AK, Abdellatif MZM, Tawfik M, Hassan EE

Toxoplasmosis is considered as an important risk factor for bad obstetric history (BOH) and one of the major causes of congenitally acquired infections. The present study aimed to estimate the...
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Toxoplasmic Lymphadenitis of the Head and Neck Region

Nam IC, Cho YJ, Jun BC, Cho KJ

Toxoplasmosis is a ubiquitous protozoan infection caused by coccidian Toxoplasma gondii. In an immunocompetent host, the primary infection is generally oligosymptomatic and self-limiting. Fewer than 10% of infected subjects are...
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Anti-Toxoplasmosis Effect of Meliae fructus Ethanol Extract

Lee HY, Kim O

Toxoplasmosis is an important cause of foodborne, inflammatory, as well as congenital abnormalities. There is an urgent need for safe and effective therapies to eliminate or treat this cosmopolitan infectious...
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