- New-Onset Fulminant Type 1 Diabetes Following SARS-CoV-2 Protein Subunit Vaccine: A Case Report and Literature Review
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Huang L, Liang M, He Y
- KMID: 2543978
- J Korean Med Sci.
- 2023 Jun;38(24):e209.
- doi: 10.3346/jkms.2023.38.e209
The ravages of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide have sped up the development of relevant vaccines, which is accompanied by public concerns over possible adverse effects. We... -
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- Field evaluation of the safety and immunogenicity of a classical swine fever virus E2 subunit vaccine in breeding and nursery animals on Jeju Island, South Korea
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Jang G, Kim EJ, Cho SC, Moon SU, Kim BS, Kim J, Jeong KJ, Song K, Mun SH, Kang WM, Lee J, Park C, Yang HS, Lee C
- KMID: 2534915
- Clin Exp Vaccine Res.
- 2022 Sep;11(3):264-273.
- doi: 10.7774/cevr.2022.11.3.264
Purpose: Classical swine fever (CSF) reemerged on CSF-free Jeju Island where vaccination is not practiced by the unintentional injection of a live attenuated vaccine (modified live attenuated vaccines–low-virulence Miyagi [MLV-LOM])... -
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- Enhanced Efficacy of Immunization with a Foot-and-Mouth Disease Multi-Epitope Subunit Vaccine Using Mannan-Decorated Inulin Microparticles
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Yoon SY, Kang SK, Lee HB, Oh SH, Kim WS, Li HS, Bok JD, Cho CS, Choi YJ
- KMID: 2509252
- Tissue Eng Regen Med.
- 2020 Feb;17(1):33-44.
- doi: 10.1007/s13770-019-00228-5
BACKGROUND: Despite the many advantages of recombinant subunit vaccines, they have critical weaknesses that include a low efficacy for promoting cellular and humoral immune responses against antigens because of their... -
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- Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0
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Oh SH, Kim Cho YS, Lee HB, Lee SM, Kim WS, Hong L, Cho CS, Choi YJ, Kang SK
- KMID: 2464086
- J Vet Sci.
- 2019 Nov;20(6):e70.
- doi: 10.4142/jvs.2019.20.e70
Porcine epidemic diarrhea (PED) is a highly contagious enteric swine disease. The large economic impact of PED on the swine industry worldwide has made the development of an effective PED... -
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- Immunogenicity and efficacy of Schmallenberg virus envelope glycoprotein subunit vaccines
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Endalew AD, Faburay B, Trujillo J, Gaudreault NN, Davis AS, Shivanna V, Sunwoo SY, Ma W, Drolet BS, McVey DS, Morozov I, Wilson WC, Richt JA
- KMID: 2464074
- J Vet Sci.
- 2019 Nov;20(6):e58.
- doi: 10.4142/jvs.2019.20.e58
The Schmallenberg virus (SBV) is an orthobunyavirus that causes abortions, stillbirths, and congenital defects in pregnant sheep and cattle. Inactivated or live attenuated vaccines have been developed in endemic countries,... -
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- Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles
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Lee HB, Yoon SY, Singh B, Oh SH, Cui L, Yan C, Kang SK, Choi YJ, Cho CS
- KMID: 2405963
- Tissue Eng Regen Med.
- 2018 Feb;15(1):1-11.
- doi: 10.1007/s13770-017-0082-x
Several barriers such as gastric pH, enzymatic degradation and rapid transit should be overcome to orally deliver antigens for taking up by epithelial microfold cells in Peyer's patches of small... -
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- Production of Recombinant Anti-Cancer Vaccines in Plants
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Lee JH, Ko K
- KMID: 2386899
- Biomol Ther.
- 2017 Jul;25(4):345-353.
- doi: 10.4062/biomolther.2016.126
Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used... -
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- Development of a Novel Subunit Vaccine Targeting Fusobacterium nucleatum FomA Porin Based on In Silico Analysis
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Jeong K, Sao P, Park MJ, Lee H, Kim SH, Rhee JH, Lee SE
- KMID: 2385807
- Int J Oral Biol.
- 2017 Jun;42(2):63-70.
- doi: 10.11620/IJOB.2017.42.2.063
Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant... -
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- Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine
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Lee SE, Nguyen CT, Kim SY, Thi TN, Rhee JH
- KMID: 2049108
- Clin Exp Vaccine Res.
- 2015 Jan;4(1):59-67.
- doi: 10.7774/cevr.2015.4.1.59
PURPOSE: Recombinant subunit vaccines provide safe and targeted protection against microbial infections. However, the protective efficacy of recombinant subunit vaccines tends to be less potent than the whole cell vaccines,... -
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- Protection of chickens from Newcastle disease with a recombinant baculovirus subunit vaccine expressing the fusion and hemagglutininneuraminidase proteins
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Lee YJ, Sung HW, Choi JG, Lee EK, Yoon H, Kim JH, Song CS
- KMID: 1718584
- J Vet Sci.
- 2008 Sep;9(3):301-308.
- doi: 10.4142/jvs.2008.9.3.301
Recombinant baculoviruses containing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein gene of the viscerotropic velogenic (vv) Newcastle disease virus (NDV) isolate, Kr-005/00, and a lentogenic La Sota strain of the... -
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- Efficacy of VP2 protein expressed in E. coli for protection against highly virulent infectious bursal disease virus
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Omar AR, Kim CL, Bejo MH, Ideris A
- KMID: 1089908
- J Vet Sci.
- 2006 Sep;7(3):241-247.
- doi: 10.4142/jvs.2006.7.3.241
The ability of a heat-inactivated whole virus from a highly virulent infectious bursal disease virus (hvIBDV) and VP2 protein from hvIBDV expressed in E. coli provided protection against a hvIBDV... -
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