- Bee venom reduces burn-induced pain via the suppression of peripheral and central substance P expression in mice
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Kang DW, Choi JG, Kim J, Park JB, Lee JH, Kim HW
- KMID: 2512438
- J Vet Sci.
- 2021 Jan;22(1):e9.
- doi: 10.4142/jvs.2021.22.e9
Background: Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives: This study examined the... -
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- Effects of endodontic treatment on salivary levels of CGRP and substance P: a pilot study
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Arslan H, Yıldız ED, Köseoğlu S
- KMID: 2512031
- Restor Dent Endod.
- 2020 Aug;45(3):e40.
- doi: 10.5395/rde.2020.45.e40
Objectives: The aim of this study was to evaluate the effects of endodontic treatment on levels of substance P (SP) and calcitonin gene-related peptide (CGRP) in the saliva of patients... -
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- Ultrastructure of Substance P Immunopositive Axons in the Human Dental Pulp
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Moon BH, Ha JH, Han HM, Kim TH, Park SK, Bae YC
- KMID: 2437353
- Int J Oral Biol.
- 2018 Sep;43(3):155-160.
- doi: 10.11620/IJOB.2018.43.3.155
There exists very little information on the ultrastructure of substance P immunopositive (+) fibers in the human dental pulp, which may help in understanding the mechanism for substance P associated... -
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- Fabrication of Microchannels and Evaluation of Guided Vascularization in Biomimetic Hydrogels
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Lee J, Lee SH, Lee BK, Park SH, Cho YS, Park Y
- KMID: 2418097
- Tissue Eng Regen Med.
- 2018 Aug;15(4):403-413.
- doi: 10.1007/s13770-018-0130-1
BACKGROUND: The fabrication of microchannels in hydrogel can facilitate the perfusion of nutrients and oxygen, which leads to guidance cues for vasculogenesis. Microchannel patterning in biomimetic hydrogels is a challenging... -
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- Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model
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Fujita M, Fukuda T, Sato Y, Takasusuki T, Tanaka M
- KMID: 2400903
- Korean J Pain.
- 2018 Jan;31(1):10-15.
- doi: 10.3344/kjp.2018.31.1.10
BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the... -
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- Substance P and Calcitonin Gene-Related Peptide in the Glands of External Auditory Canal Skin
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Yoon YJ, Yoon J, Lee EJ, Kim JS
- KMID: 2396786
- Clin Exp Otorhinolaryngol.
- 2017 Dec;10(4):321-324.
- doi: 10.21053/ceo.2017.00129
OBJECTIVES: The earwax (cerumen) that covers external auditory canal (EAC) skin contains a mixture of ceruminous and sebaceous gland substances, such as lipids, peptides, and proteins. The components secreted from... -
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- Intravenous Administration of Substance P Attenuates Mechanical Allodynia Following Nerve Injury by Regulating Neuropathic Pain-Related Factors
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Chung E, Yoon TG, Kim S, Kang M, Kim HJ, Son Y
- KMID: 2378803
- Biomol Ther.
- 2017 May;25(3):259-265.
- doi: 10.4062/biomolther.2016.137
This study aimed to investigate the analgesic effect of substance P (SP) in an animal model of neuropathic pain. An experimental model of neuropathic pain, the chronic constriction injury (CCI)... -
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- Substance P and Thiorphan Synergically Enhance Angiogenesis in Wound Healing
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Um J, Yu J, Dubon MJ, Park KS
- KMID: 2360854
- Tissue Eng Regen Med.
- 2016 Apr;13(2):149-154.
- doi: 10.1007/s13770-016-9089-y
Impaired angiogenesis is a common pathological characteristic of chronic wounds. Therefore, the regulation of angiogenesis is important for proper tissue repair. It was reported that substance P (SP) accelerates wound... -
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- Olopatadine ophthalmic solution suppresses substance P release in the conjunctivitis models
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Tamura T
- KMID: 2397364
- Asia Pac Allergy.
- 2012 Apr;2(2):115-121.
- doi: 10.5415/apallergy.2012.2.2.115
BACKGROUND: Olopatadine hydrochloride ophthalmic solutions are treated for allergic conjunctival diseases that are a selective histamine H1 receptor antagonist and an inhibitor of the release of mediators including histamine from... -
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- Silk Fibroin and Substance P Combination Graft for the Reconstruction of a Bone Defect
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Park KY, Choi KH, Park YJ, Song JY, Kim SG, Jo YY, Kweon HY, Kang SW
- KMID: 2009670
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2011 Jul;33(4):293-300.
PURPOSE: Substance P is a well known neurotransmitter and has been known to mediate pain. Recently, it has been unveiled that substance P is involved in the recruitment of mesenchymal... -
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- The effect of tumor necrosis factor (TNF)-alpha to induce matrix metalloproteinase (MMPs) from the human dental pulp, gingival, and periodontal ligament cells
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Rhim EM, Park SH, Kim DS, Kim SY, Choi KK, Choi GW
- KMID: 1446081
- J Korean Acad Conserv Dent.
- 2011 Jan;36(1):26-36.
- doi: 10.5395/JKACD.2011.36.1.26
OBJECTIVES: In the present study, three kinds of tissues cells (pulp, gingiva, and periodontal ligament) were investigated if those cells express MMP and TIMP when they were stimulated with neuropeptides... -
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- Viewpoints on Acid-Induced Inflammatory Mediators in Esophageal Mucosa
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Harnett KM, Rieder F, Behar J, Biancani P
- KMID: 2204233
- J Neurogastroenterol Motil.
- 2010 Oct;16(4):374-388.
We have focused on understanding the onset of gastroesophageal reflux disease by examining the mucosal response to the presence of acid in the esophageal lumen. Upon exposure to HCl, inflammation... -
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- Neurokinin and Its Receptors: Association with Learning and Memory
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Kim MD, Lee CI
- KMID: 2287030
- Korean J Psychopharmacol.
- 2007 Sep;18(5):280-287.
The neurokinin Substance P is widely distributed in the central nervous system and has been extensively studied in various functional aspects. Substance P has been reported to have memory-promoting, reinforcing,... -
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- Nerve Ingrowth into Intervertebral Disc in Internal Disc Disruption
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Shin JH, Seo JY, Ha KY
- KMID: 2322934
- J Korean Soc Spine Surg.
- 2006 Dec;13(4):275-283.
STUDY DESIGN: The ingrowth of the nociceptive nerve ending into intervertebral disc was examined using immunohistochemistry and quantified using western blotting. OBJECTIVES: To determine if the nociceptive nerve innervates into the... -
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- Detection of Substance P, Calcitonin Gene-Related Peptide and Prostaglandin E2 in Human Epidural Space
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Paek SH, Kim HT, Kim BI
- KMID: 2073924
- Korean J Pain.
- 2006 Dec;19(2):168-174.
- doi: 10.3344/kjp.2006.19.2.168
BACKGROUND: Several biochemical mediators, such as substance P, calcitonin gene-related peptide (CGRP) and prostaglandin E2, have been demonstrated to be involved in herniated or degenerated disc-induced radiculopathy. The authors... -
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- Immunohistochemical localization of calcium binding proteins and some neurotransmitters in myenteric plexus of goat stomach
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Lee HS, Nam YS
- KMID: 1089476
- J Vet Sci.
- 2006 Dec;7(4):315-319.
- doi: 10.4142/jvs.2006.7.4.315
To understand the neurochemical properties of the gastric myenteric plexus of ruminants, the expression patterns of calbindin D-28k (CB), calretinin (CR), substance P (SP) and calcitonin gene-related peptide (CGRP) were... -
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- Hypoxia-A Possibility in Fibromyalgia Syndrome Pathogenesis
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Kim SH, Moon IS
- KMID: 2202233
- J Korean Rheum Assoc.
- 2006 Sep;13(3):218-225.
OBJECTIVE: We studied the expression of pain-related molecules such as substance P involved in chronic pain of fibromyalgia syndrome (FMS) patients using rat cortical cells in hypoxia. METHODS: We sacrificed pregnant... -
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- A study of neuropeptides related to headaches in children with meningeal irritation signs
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Seo BG, Yoo MH, Shim JW, Shim JY, Jung HL, Park MS, Kim DS
- KMID: 2278571
- Korean J Pediatr.
- 2006 May;49(5):533-538.
- doi: 10.3345/kjp.2006.49.5.533
PURPOSE: The headache, one of the symptoms of meningitis, is related to abrupt elevation of intracranial pressure(ICP) or stimulation of intracranial nociceptive structure. However, in cases of mild elevation of... -
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- The effect of neuropeptides on secretion of Interleukin-8 (IL-8)
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Kim KJ, Park SH, Choi KK, Park SJ
- KMID: 2175814
- J Korean Acad Conserv Dent.
- 2006 May;31(3):153-160.
- doi: 10.5395/JKACD.2006.31.3.153
We investigated the secretion of Interleukin-8 (IL-8) from ginviva and periodontal ligament stimulated with Substance P (SP) and Calcitonin Gene-related Peptide (CGRP). Gingiva (GF), periodontal ligament (PDLF) and pulp (PF)... -
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- Expression of Substance P in the Experimental Diabetic Rat Retina
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Lee SM, Park SJ, Kang TH, Chung JW, Chun MH, Oh SJ
- KMID: 1937827
- Korean J Anat.
- 2006 Apr;39(2):159-167.
Substance P (Sub P) being composed of 11 amino acids sequence is a kind of tachykinin family peptides. It has been known that this substance plays a role of neurotransmitter... -
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