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Exercise/Resistance Training and Muscle Stem Cells

Fukada Si, Nakamura A

Skeletal muscle has attracted attention as endocrine organ, because exercise-dependent cytokines called myokines/exerkines are released from skeletal muscle and are involved in systemic functions. While, local mechanical loading to skeletal...
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Effects of intragastric balloon on obesity in obese Korean women for 6 months post removal

Pak HJ, Choi HN, Lee HC, Yim JE

BACKGROUND/OBJECTIVES: The prevalence of morbid obesity in Korean women has consistently been increasing, while the overall prevalence rate of obesity in Korean women seems to be stable. In addition to...
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Relationship between Skeletal Muscle Mass, Bone Mineral Density, and Trabecular Bone Score in Osteoporotic Vertebral Compression Fractures

Tokeshi S, Eguchi Y, Suzuki M, Yamanaka H, Tamai H, Orita S, Inage K, Shiga Y, Hagiwara S, Nakamura J, Akazawa T, Takahashi H, Ohtori S

Study Design A retrospective observational study was performed. Purpose We investigated the relationships between skeletal muscle mass, bone mineral density (BMD), and trabecular bone score (TBS) in patients with osteoporotic vertebral compression fractures...
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Comparison of skeletal muscle index-based formula and body surface area-based formula for calculating standard liver volume

Yang G, Hwang S, Song GW, Jung DH

Backgrounds/Aims: Formula-derived standard liver volume (SLV) has been clinically used for living donor liver transplantation and hepatic resection. The majority of currently available SLV formulae are based on body surface...
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Association between dietary branchedchain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity

Chae M, Park HS, Park K

BACKGROUND/OBJECTIVES: The branched-chain amino acids (BCAA), including isoleucine, leucine, and valine, promote muscle protein synthesis. However, obesity may interfere with protein synthesis by dysregulating mitochondrial function in the muscles. This study...
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Impact of appendicular and trunk skeletal muscle mass and back extensor strength on sagittal spinal alignment in Japanese women without vertebral fracture

Kudo D, Miyakoshi N, Hongo M, Kasukawa Y, Ishikawa Y, Mizutani T, Mizutani Y, Shimada Y

Objectives: Progressive and generalized loss of skeletal muscle mass (SMM) and strength are characteristics of sarcopenia. However, the impact of appendicular and trunk SMM and back extensor strength (BES) on...
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Tail suspension is useful as a sarcopenia model in rats

Nemoto A, Goyagi T

Background Sarcopenia promotes skeletal muscle atrophy and exhibits a high mortality rate. Its elucidation is of the highest clinical importance, but an animal experimental model remains controversial. In this study, we...
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Early high-fat feeding improves histone modifications of skeletal muscle at middle-age in mice

Yoshie T, Saito C, Kawano F

The purpose of the present study was to investigate how the effects of high-fat diet feeding on the skeletal muscle persisted during aging using mice. Post-weaned male mice were fed...
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Sarcopenia in women with hip fracture: A comparison of hormonal biomarkers and their relationship to skeletal muscle mass and function

Yee ML, Hau R, Taylor A, Guerra M, Guerra P, Darzins P, Gilfillan C

Objectives: Sarcopenia is a decline in skeletal muscle mass and function. It is associated with adverse outcomes and increased mortality. Sarcopenia is also reported to be prevalent in the hip...
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The lumbar multifidus is characterised by larger type I muscle fibres compared to the erector spinae

Agten A, Stevens S, Verbrugghe J, Eijnde BO, Timmermans A, Vandenabeele F

The metabolic capacity of a muscle is one of the determinants of muscle function. Muscle fiber type characteristics give an indication about this metabolic capacity. Therefore it might be expected...
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Association of height loss with falls and sarcopenia in communitydwelling older women

Asahi R, Yuguchi S, Kamo T, Azami M, Ogihara H, Asano S

Objectives: Height loss is associated with vertebral fracture risk and osteoporosis. We assumed that height loss may indicate the risk of falls because the presence of osteoporosis is significantly associated...
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Effect of Stem Cells, Ascorbic Acid and SERCA1a Gene Transfected Stem Cells in Experimentally Induced Type I Diabetic Myopathy

Zickri MB, Sadek EM, Fares AE, Heteba NG, Reda AM

Background and Objectives: Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) inhibition was proved in streptozotocin (STZ)-diabetic rats. The present study aimed at investigating and comparing the therapeutic effect of bone marrow mesenchymal stem...
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Suggested Assessments for Sarcopenia in Patients With Stroke Who Can Walk Independently

Jung HJ, Lee YM, Kim M, Uhm KE, Lee J

Objective To investigate variables for assessment of stroke-related sarcopenia that are alternative options to the current assessment for sarcopenia, which focuses on age-related sarcopenia and also has limitations in addressing...
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Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study

Anand A, Shetty AP, Renjith KR, K. S. SVA, Kanna RM, Rajasekaran S

Study Design: Case-control study. Purpose: Sarcopenia is an age associated condition characterized by decrease in muscle mass, strength, and physical performance. We aimed to investigate whether sarcopenia increased the risk of...
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Mechanical Properties of Single Muscle Fibers: Understanding Poor Muscle Quality in Older Adults with Diabetes

Lee EJ, Jang HC, Koo KH, Kim HY, Lim JY

Background: While aging causes muscle weakness, type 2 diabetes mellitus (T2DM) is also considered a high-risk factor for the induction of skeletal muscle weakness. Previous studies have reported increased collagen...
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Sarcopenia and Muscle Aging: A Brief Overview

Dao T, Green AE, Kim YA, Bae SJ, Ha KT, Gariani K, Lee Mr, Menzies KJ, Ryu D

The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a...
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Pharmacological Interventions for Treatment of Sarcopenia: Current Status of Drug Development for Sarcopenia

Kwak JY, Kwon KS

Sarcopenia, the loss of skeletal muscle mass and function with age, was first recognized as a disease in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) (M62.84) and...
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Effectiveness of ultrasonographic skeletal muscle assessment in patients after total knee arthroplasty

Kitsuda Y, Tanimura C, Inoue K, Park D, Osaki M, Hagino H

OBJECTIVES: This study aimed to characterize the skeletal muscles of patients who underwent total knee arthroplasty (TKA) using ultrasonography in order to investigate the effectiveness of ultrasonographic skeletal muscle assessment...
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MBP-FGF2-Immobilized Matrix Maintains Self-Renewal and Myogenic Differentiation Potential of Skeletal Muscle Stem Cells

Sah JP, Hao NT, Kim Y, Eigler T, Tzahor E, Kim SH, Hwang Y, Yoon JK

The robust capacity of skeletal muscle stem cells (SkMSCs, or satellite cells) to regenerate into new muscles in vivo has offered promising therapeutic options for the treatment of degenerative muscle...
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Contrast Enhanced Ultrasound Perfusion Imaging in Skeletal Muscle

Nguyen T, Davidson B

The ability to accurately evaluate skeletal muscle microvascular blood flow has broad clinical applications for understanding the regulation of skeletal muscle perfusion in health and disease states. Contrast-enhanced ultrasound (CEU)...
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