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The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC

Liu F, Long D, Huang W, Peng W, Lan H, Zhou Y, Dang X, Zhou R

Background and Objectives: Although human-induced pluripotent stem cells (hiPSC) can be efficiently differentiated into cardiomyocytes (CMs), the heterogeneity of the hiPSC-CMs hampers their applications in research and regenerative medicine. Retinoic...
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Function and Dysfunction of Human Sinoatrial Node

Joung B, Chen PS

Sinoatrial node (SAN) automaticity is jointly regulated by a voltage (cyclic activation and deactivation of membrane ion channels) and Ca2+ clocks (rhythmic spontaneous sarcoplasmic reticulum Ca2+ release). Using optical mapping...
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RE: An Unusual Course of Right Coronary Artery Originating from Sinoatrial Node Artery

Kara K, Ozturk E, Saglam M

No abstract available.
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Coronary-to-Bronchial Artery Fistula Originating from the S-Shaped Sinoatrial Node Artery: CT and Angiography Findings

Beck KS, Lee BY, Cho EJ

Coronary artery fistula (CAF) is a rare type of anomaly in which a fistulous connection between a coronary artery and another vascular structure is present. Even among CAFs, a connection...
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IgG4-Related Sclerosing Disease Involving the Superior Vena Cava and the Atrial Septum of the Heart

Song C, Koh MJ, Yoon YN, Joung B, Kim SH

A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and...
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Anatomy of the Sinoatrial Nodal Branch in Korean Population: Imaging with MDCT

Song YS, Lee W, Park EA, Chung JW, Park JH

OBJECTIVE: To evaluate, on a retrospective basis, the anatomic characteristics of the arterial supply to the sinoatrial node (SAN) in the Korean population using an ECG-gated multi-detector CT (MDCT). MATERIALS AND...
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Heart Rate Acceleration of a Subsidiary Pacemaker by beta-Adrenergic Stimulation

Park S, Park H, Hwang HJ, Shim J, Sung JH, Kim JY, Pak HN, Lee MH, Joung B

BACKGROUND AND OBJECTIVES: Recent evidence indicates that the membrane voltage and Ca2+ clocks jointly regulate sinoatrial node (SAN) automaticity. However, the mechanism of heart rhythm acceleration of the subsidiary pacemaker...
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The Role of the Calcium and the Voltage Clocks in Sinoatrial Node Dysfunction

Joung B, Chen PS, Lin SF

Recent evidence indicates that the voltage clock (cyclic activation and deactivation of membrane ion channels) and Ca2+ clocks (rhythmic spontaneous sarcoplasmic reticulum Ca2+ release) jointly regulate sinoatrial node (SAN) automaticity....
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The Calcium and Voltage Clocks in Sinoatrial Node Automaticity

Joung B, Ogawa M, Lin SF, Chen PS

Recent evidence indicates that the voltage (cyclic activation and deactivation of membrane ion channels) and Ca2+ clocks (rhythmic spontaneous sarcoplasmic reticulum Ca2+ release) jointly regulate sinoatrial node (SAN) automaticity. Since...
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Two Case Reports of Sudden Unexpected Death Resulting from Inflammation of the Sinoatrial node

Park HJ, Kwon TJ, Jeon SH

  • KMID: 2250455
  • Korean J Leg Med.
  • 2002 Oct;26(2):56-59.
Sudden unexpected deaths with noncontributory histories, autopsy results, and drug screen results are a common problem in forensic pathology. In particular, no evidence of macroscopic cardiac abnormalities can be observed....
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The Gradient Model of the Rabbit Sinoatrial Node

Dobrzynski H, Lei M, Jones SA, Lancaster , Boyett MR

  • KMID: 2071577
  • Korean J Physiol Pharmacol.
  • 2002 Aug;6(4):173-182.
The sinoatrial (SA) node is a complex and inhomogeneous tissue in terms of cell morphology and electrical activity. There are two models of the cellular organisation of the sinoatrial node:...
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