- Acute and 28-days subacute toxicity studies of Gαq-RGS2 signaling inhibitor
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Beladiya JV, Mehta AA
- KMID: 2521034
- Lab Anim Res.
- 2021 Sep;37(3):193-202.
- doi: 10.1186/s42826-021-00093-1
Background: The aim of study was to evaluate the single oral dose and 28 day repeated oral administration toxicity profile of the synthetic compound Gαq-RGS2 signaling inhibitor, (1-(5-chloro-2-hydroxyphenyl)-3-(4-(trifluoromethyl)phenyl)-1 H-1,2,4-triazol-5(4 H)-one)... -
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- Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder
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Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH
- KMID: 2317845
- Toxicol Res.
- 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as... -
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- Single Oral Dose Toxicity Study of Prebrewed Armeniacae Semen in Rats
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Park JH, Seo BI, Cho SY, Park KR, Choi SH, Han CK, Song CH, Park SJ, Ku SK
- KMID: 2317821
- Toxicol Res.
- 2013 Jun;29(2):91-98.
Armeniacae semen (AS) has been considered a toxic herb in the Korean medicine as it contains hydrogen cyanide and amygdalin, especially in its endocarp. Therefore, prebrewed AS that is devoid... -
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- Mouse Single Oral Dose Toxicity Test of Bupleuri Radix Aqueous Extracts
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Kim KH, Gam CO, Choi SH, Ku SK
- KMID: 2052546
- Toxicol Res.
- 2012 Mar;28(1):11-18.
The aim of this study was to evaluate the single oral dose toxicity of Bupleuri Radix (BR) aqueous extracts, it has been traditionally used as anti-inflammatory agent, in male and... -
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- Biological Activity and Single Oral Dose Toxicity of Dansam-samultang
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Lee IC, Kim BH, Kim MK
- KMID: 2114707
- Lab Anim Res.
- 2010 Dec;26(4):385-391.
- doi: 10.5625/lar.2010.26.4.385
In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Dansam-samultang to evaluate its use as a functional ingredient... -
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- Investigations of Samwhang-sasimtang Extracts on Biological Activities In Vitro and Vivo
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Lee IC, Kim BH, Kim MK
- KMID: 1458935
- Lab Anim Res.
- 2010 Mar;26(1):15-20.
- doi: 10.5625/lar.2010.26.1.15
In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Samwhang-sasimtang to evaluate its use as a functional ingredient... -
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