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Does Listening to Tinnitus Frequency-Filtered Music Relieve Tinnitus?

Yoo S, Yakunina N, Nam EC

Background and Objectives: Tinnitus frequency-filtered music therapy aims to restore lateral inhibition to reverse tonotopic reorganization in the auditory cortex. Although the tinnitus-relieving effect of this therapy has been investigated,...
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Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study

Yoon EL, Ahn SB, Jun DW, Cho YK, Song DS, Jeong JY, Kim HY, Jung YK, Song MJ, Kim SE, Kim HS, Jeong SW, Kim SG, Lee TH

Background/Aims: L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with...
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Anti-adhesive effect and safety of a thermosensitive adhesion barrier (Mediclore) for thyroid surgery: a double-blinded randomized controlled trial

Ahn Jh, Yoon SG, Yi JW, Kim Sj, Lee KE

Purpose: Postoperative adhesions after thyroidectomy adversely affect patients’ quality of life. This study assessed the anti-adhesive effect and safety of thermosensitive sol-gel agents for patients undergoing thyroidectomy. Methods: A double-blind parallel-group...
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The effect of fibrin glue on the quantity of drainage after thyroidectomy: a randomized controlled pilot trial

Ha EJ, Lee J

Purpose: A seroma is a collection of exudates after surgical trauma in wound healing. Fibrin glue is used to prevent seroma by reducing the generation of exudate. However, the impact...
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Adductor canal block versus intra-articular steroid and lidocaine injection for knee osteoarthritis: a randomized controlled study

Ming LH, Chin CS, Yang CT, Suhaimi A

Background: This study aimed to assess the efficacy of the adductor canal block (ACB) in comparison to intra-articular steroid-lidocaine injection (IASLI) to control chronic knee osteoarthritis (KOA) pain. Methods: A randomized,...
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A Systematic Review of Randomized Controlled Trials of Antibiotic Use in Diabetic Foot Ulcer Infections: Focus on Clinical Cure

Pratama V, Risni HW, Yunir E, Sauriasari R

Background: The use of antibiotics in diabetic foot ulcer infections (DFUI) is essential in reducing morbidity. Optimal administration of antibiotics can improve clinical outcomes and reduce the risk of antibiotic...
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Long-Term Follow-up of Enhanced Holter-Electrocardiography Monitoring in Acute Ischemic Stroke

Wachter R, Weber-Krüger M, Hamann GF, Kermer P, Liman J, Mende M, Seegers J, Wasser K, Gröschel S, Uphaus T, Poppert H, Köhrmann M, Zabel M, Laufs U, Heuschmann PU, Conen D, Gröschel K, on Behalf of the Find-AFRANDOMISED Investigators and Coordinators

Background and Purpose Prolonged electrocardiography (ECG)-monitoring in stroke patients improves the detection of paroxysmal atrial fibrillation (pAF). However, most randomized studies only had short follow-up. We aimed to provide 3-year...
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Efficacy and Safety of Self-Titration Algorithms of Insulin Glargine 300 units/mL in Individuals with Uncontrolled Type 2 Diabetes Mellitus (The Korean TITRATION Study): A Randomized Controlled Trial

Bae JH, Ahn CH, Yang YS, Moon SJ, Kwak SH, Jung HS, Park KS, Cho YM

Background: To compare the efficacy and safety of two insulin self-titration algorithms, Implementing New Strategies with Insulin Glargine for Hyperglycemia Treatment (INSIGHT) and EDITION, for insulin glargine 300 units/mL (Gla-300)...
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Efficacy and safety of hydroxychloroquine in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

Singh A, Kotlo A, Wang Z, Dissanayaka T, Das S, Antony B

Background/Aims: Conventional disease-modifying anti-rheumatic drugs have been trialed in osteoarthritis (OA). Hydroxychloroquine (HCQ), which has shown its effectiveness in rheumatoid arthritis, has been trialed for the treatment of OA; however,...
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Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments

Xia T, Zhao F, Nianogo RA

Background: Hypertension is an urgent public health problem. Consistent summary from natural and quasiexperiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current...
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Developing and Evaluating a Mobile-based Parental Education Program for Preventing Unintentional Injuries in Early Childhood: A Randomized Controlled Trial

Choi Y, Ahn HY

Purpose This randomized controlled experimental study verified the educational effect of a mobile-based parental education program for preventing unintentional early childhood injuries. Methods (Design and Methods) From August 2019 to September 2019,...
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When and why to start continuous renal replacement therapy in critically ill patients with acute kidney injury

An JN, Kim SG, Song YR

Acute kidney injury (AKI) is a common condition in critically ill patients, and may contribute to significant medical, social, and economic consequences, including death. Although there have been advances in...
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No-Touch vs. Conventional Radiofrequency Ablation Using Twin Internally Cooled Wet Electrodes for Small Hepatocellular Carcinomas: A Randomized Prospective Comparative Study

Suh YS, Choi JW, Yoon JH, Lee DH, Kim YJ, Lee JH, Yu SJ, Cho EJ, Yoon JH, Lee JM

Objective: This study aimed to compare the efficacy between no-touch (NT) radiofrequency ablation (RFA) and conventional RFA using twin internally cooled wet (TICW) electrodes in the bipolar mode for the...
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Erector spinae plane block for spinal surgery: a systematic review and meta-analysis

Liang X, Zhou W, Fan Y

Background: Although the erector spinae plane block has been used in various truncal surgical procedures, its clinical benefits in patients undergoing spinal surgery remain controversial. The aim of this meta-analysis...
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Mixed- versus predilution hemodiafiltration effects on convection volume and small and middle molecule clearance in hemodialysis patients: a prospective randomized controlled trial

Park KS, Kang EW, Chang TI, Jo W, Park JT, Yoo TH, Kang SW, Han SH

Background: The use of newly developed mixed-dilution hemodiafiltration (HDF) can supplement the weaknesses of pre- and postdilution HDF. However, it is unclear whether mixed-HDF performs well compared to predilution HDF....
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Behavioral therapy and pharmacotherapy for relapse prevention in abstinent smokers: a rapid review and meta-analysis for the Korea Preventive Service Task Force

Lee N, Lee ES, Yun JM, Lee CM, Oh SW, Choi Y, Cho B

Objectives This study aimed to assess the effectiveness of relapse prevention interventions involving behavioral and pharmacological treatment among abstinent smokers. Methods This rapid review was conducted using MEDLINE, Cochrane CENTRAL, CINAHL, Embase, KMbase,...
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The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis

Manchikanti L, Knezevic E, Knezevic NN, Sanapati MR, Kaye AD, Thota S, Hirsch JA

Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases,...
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The Effects of Exercise Intervention for Post-Operative Breast Cancer Patients in Korea: A Systemic Review and Meta-Analysis of Randomized Controlled Trials

Lee Ds, Kim Hs, Choi So, Kim Em

Purpose: This study aimed to systematically evaluate literature related to the effects of exercise intervention programs on physical or psychological variables of post-operative breast cancer patients in Korea, and identify...
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Comparison of sandblasted and acid-etched surface implants and new hydrophilic surface implants in the posterior maxilla using a 3-month early-loading protocol: a randomized controlled trial

Kim HG, Yun PY, Kim YK, Kim Ih

Objectives: In this prospective randomized controlled trial, we measured the primary and secondary stability of two surface-treated implants placed in the posterior maxilla, applied 3-month loading protocols, and compared and...
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Effectiveness of tramadol compared to lignocaine as local anesthesia in the extraction of firm teeth: a randomized controlled trial

Goel M, Sen P, Maturkar T, Latke S, Dehankar T

Background: The aim of this study was to compare the local anesthetic effect of tramadol with that of lignocaine in the extraction of immobile (grade 0) maxillary first molars. Methods: This...
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